The Third Coast Center for AIDS Research (TC CFAR) partners Northwestern University (NU), the University of Chicago (UC), and the Chicago Department of Public Health (CDPH). Participating community organizations include the Alliance of Chicago Community Health Services (the Alliance), the Center on Halsted (COH), and the AIDS Foundation of Chicago (AFC). The Third Coast CFAR will Make big plans;
aim high in hope and work (Daniel Burnham). The Cores will provide services and assays to enable all fields of HIV research to contribute to ending the epidemic (Clinical Sciences (CS) Core; Behavioral, Social, and Implementation Sciences (BSIS) Core; Viral Pathogenesis (VP) Core), as well as leadership, communication, networking, seed funding, and mentoring (Administrative and Developmental Cores). A Scientific Working Group called Chicago Uniting on Research to End HIV (END HIV) will catalyze new teams combining biomedical and behavioral researchers. The SWG and the Cores will help these teams engage the community in focusing on the leading edge of the epidemic in young men who have sex with men (YMSM). The long term goals are to develop new approaches to decrease HIV incidence among YMSM now having annually increasing rates of diagnoses, as well as to improve the continuum of care and opportunities for participation in novel research aimed at achieving more prolonged sustained remissions after early antiretroviral treatment for those who become infected. Third Coast CFAR members have proven track records leading evidence-based, community-engaged translational research to improve the health of the lesbian, gay, bisexual, and transgender (LGBT) community. They innovate new biomedical prevention, diagnostic, and treatment modalities for HIV, as well as advancing biological science through cutting-edge research on immunopathogenesis, imaging, genomics, and bioengineering. Our members advance network and implementation science as well as social science and policy research / advocacy. TC CFAR faculty led highly productive multi-center collaborations and are experienced in partnering with public health experts and disseminating new knowledge to the community. The TC CFAR will add value to our existing strong research portfolio by scientific leadership and strategic planning that builds synergistic new collaborations, enhances community engagement on HIV research and health, and supports innovation and research productivity.

Public Health Relevance

The Third Coast Center for AIDS Research leverages complementary strengths of Northwestern University, the University of Chicago, the Chicago Department of Public Health and community organizations across Chicago to enable a comprehensive infrastructure for multi-disciplinary, collaborative HIV research. This unique and catalytic integration of all topics and disciplines of HIV-related research will maximize positive impacts on public health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
1P30AI117943-01
Application #
8899204
Study Section
Special Emphasis Panel ()
Program Officer
Beaubien, Candice M
Project Start
2015-04-09
Project End
2020-03-31
Budget Start
2015-04-09
Budget End
2016-03-31
Support Year
1
Fiscal Year
2015
Total Cost
$936,990
Indirect Cost
$288,870
Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Mustanski, Brian; Parsons, Jeffrey T; Sullivan, Patrick S et al. (2018) Biomedical and Behavioral Outcomes of Keep It Up!: An eHealth HIV Prevention Program RCT. Am J Prev Med 55:151-158
Addington, Elizabeth L; Cheung, Elaine O; Moskowitz, Judith T (2018) Positive affect skills may improve pain management in people with HIV. J Health Psychol :1359105318769355
Procter, Dean J; Banerjee, Avik; Nukui, Masatoshi et al. (2018) The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread. Dev Cell 45:83-100.e7
Blass, Eryn; Aid, Malika; Martinot, Amanda J et al. (2018) Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection. J Virol 92:
Nakashima, Hiroshi; Alayo, Quazim A; Penaloza-MacMaster, Pablo et al. (2018) Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells. Sci Rep 8:208
Meade, Nathan; Furey, Colleen; Li, Hua et al. (2018) Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit. Cell 174:1143-1157.e17
Rael, Christine Tagliaferri; Martinez, Michelle; Giguere, Rebecca et al. (2018) Barriers and Facilitators to Oral PrEP Use Among Transgender Women in New York City. AIDS Behav 22:3627-3636
Badamchi-Zadeh, Alexander; Moynihan, Kelly D; Larocca, Rafael A et al. (2018) Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. J Immunol 201:2744-2752
Bhattacharyya, Mitra; Whitney, James B; Seaman, Michael et al. (2018) T-cell subset differentiation and antibody responses following antiretroviral therapy during simian immunodeficiency virus infection. Immunology 155:458-466
Gianella, Sara; Marconi, Vincent C; Berzins, Baiba et al. (2018) Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy. J Acquir Immune Defic Syndr 79:e112-e114

Showing the most recent 10 out of 51 publications