Therapy have joined together to form a core of multi-disciplinary researchers focusing on the quantitative development of musculo-skeletal imaging. The Musculoskeletal and Quantitative Imaging Research (MQIR) Core proposes to develop a proposal in response to RFA-OD-09-005. This P30 RFA is to support the hiring of newly recruited faculty to develop research projects within the context of MQIR Core Center. We propose to enhance this core with three key.faculty recruitments. An imaging scientist, focusing on molecular and functional imaging, of small animals, especially focused on animal models of musculo-skeletal degeneration, pathologies and regeneration. A faculty position focused on developing imaging techniques, utilizing these technologies for quantitative modeling, in conjunction with gait analysis, biomechanics and human performance. A magnetic resonance imaging scientist who will focus on developing novel translational imaging and image processing methodologies, with primary focus on the instrumentation at the Orthopedics Institute. In addition, funds will be sought for technicians, student and post-doctoral researcher support, and to cover use of core recharges to develop pilot projects. Funds to cover imaging time will also be made available through the Department of Radiology Seed Grant program and Pilot funding programs. Each department will commit to the support of one faculty position for the two years after the P30 grant, should the faculty member hired need the support.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
5P30AR058899-02
Application #
7943916
Study Section
Special Emphasis Panel (ZAR1-EHB-F (M2))
Program Officer
Tyree, Bernadette
Project Start
2009-09-30
Project End
2012-08-31
Budget Start
2010-09-01
Budget End
2012-08-31
Support Year
2
Fiscal Year
2010
Total Cost
$486,710
Indirect Cost
Name
University of California San Francisco
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Teng, H-L; Calixto, N E; MacLeod, T D et al. (2016) Associations between patellofemoral joint cartilage T1? and T2 and knee flexion moment and impulse during gait in individuals with and without patellofemoral joint osteoarthritis. Osteoarthritis Cartilage 24:1554-64
Han, Misung; Chiba, Ko; Banerjee, Suchandrima et al. (2015) Variable flip angle three-dimensional fast spin-echo sequence combined with outer volume suppression for imaging trabecular bone structure of the proximal femur. J Magn Reson Imaging 41:1300-10
Nardo, Lorenzo; Karampinos, Dimitrios C; Lansdown, Drew A et al. (2014) Quantitative assessment of fat infiltration in the rotator cuff muscles using water-fat MRI. J Magn Reson Imaging 39:1178-85
Karampinos, Dimitrios C; Melkus, Gerd; Baum, Thomas et al. (2014) Bone marrow fat quantification in the presence of trabecular bone: initial comparison between water-fat imaging and single-voxel MRS. Magn Reson Med 71:1158-65
Nardo, Lorenzo; Sandman, David N; Virayavanich, Warapat et al. (2013) Bone marrow changes related to disuse. Eur Radiol 23:3422-31
Subburaj, Karupppasamy; Valentinitsch, Alexander; Dillon, Alexander B et al. (2013) Regional variations in MR relaxation of hip joint cartilage in subjects with and without femoralacetabular impingement. Magn Reson Imaging 31:1129-36
Souza, Richard B; Fang, Charles; Luke, Anthony et al. (2012) Relationship between knee kinetics during jumping tasks and knee articular cartilage MRI T1rho and T2 relaxation times. Clin Biomech (Bristol, Avon) 27:403-8
Krug, Roland; Larson, Peder Eric Zufall; Wang, Chunsheng et al. (2011) Ultrashort echo time MRI of cortical bone at 7 tesla field strength: a feasibility study. J Magn Reson Imaging 34:691-5
Carballido-Gamio, Julio; Folkesson, Jenny; Karampinos, Dimitrios C et al. (2011) Generation of an atlas of the proximal femur and its application to trabecular bone analysis. Magn Reson Med 66:1181-91
Krug, Roland; Burghardt, Andrew J; Majumdar, Sharmila et al. (2010) High-resolution imaging techniques for the assessment of osteoporosis. Radiol Clin North Am 48:601-21