- BIOSTATISTICS SHARED RESOURCE The increasing variety and complexity of data types, analytic approaches and study designs utilized in cancer research necessitate the availability of an organized and centralized biostatistics resource that can offer a wide range of statistical expertise, collaboration, and training opportunities to investigators at the Albert Einstein Cancer Center (AECC). The Biostatistics Shared Resource (BSR) is staffed by experienced statisticians with strong track records in effective collaboration across all scientific programs, innovative research in cancer relevant statistical areas, and training and mentoring investigators at all levels. BSR personnel have critical roles in enhancing the Center infrastructure and fostering multi-disciplinary team science given their broad knowledge of the scope of research activities within the AECC and active involvement on various cancer center committees. The specific objectives of the BSR are: (i) To provide state-of-the-art statistical support on all phases of cancer research, from experimental design and study conduct to data analysis and manuscript preparation; (ii) To collaborate on the development of methodologically rigorous grant applications and new research initiatives; (iii) To assist with the development and scientific review of clinical trial protocols; (iv) To develop innovative statistical approaches for new technologies in cancer research; (v) To offer a variety of training opportunities in statistical methods to AECC members and to mentor junior cancer investigators; (vi) To enhance the AECC infrastructure and foster interdisciplinary collaborations via participation on scientific and administrative committees and interactions with other shared resources. The overall goal in accomplishing these objectives is to provide a robust, comprehensive and cost-effective system of statistical support for AECC investigators that contributes significantly to advancing the understanding of cancer etiologies and prognosis, as well as improving cancer prevention, detection and treatment strategies.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Albert Einstein College of Medicine
United States
Zip Code
Dulyaninova, Natalya G; Ruiz, Penelope D; Gamble, Matthew J et al. (2018) S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms. Mol Biol Cell 29:632-642
Chen, Zigui; Schiffman, Mark; Herrero, Rolando et al. (2018) Classification and evolution of human papillomavirus genome variants: Alpha-5 (HPV26, 51, 69, 82), Alpha-6 (HPV30, 53, 56, 66), Alpha-11 (HPV34, 73), Alpha-13 (HPV54) and Alpha-3 (HPV61). Virology 516:86-101
Heo, Moonseong; Kim, Namhee; Rinke, Michael L et al. (2018) Sample size determinations for stepped-wedge clinical trials from a three-level data hierarchy perspective. Stat Methods Med Res 27:480-489
Kunnath-Velayudhan, Shajo; Porcelli, Steven A (2018) Isolation of intact RNA from murine CD4+ T cells after intracellular cytokine staining and fluorescence-activated cell sorting. J Immunol Methods 456:77-80
Zamurrad, Sumaira; Hatch, Hayden A M; Drelon, Coralie et al. (2018) A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5. Cell Rep 22:2359-2369
Sparano, Joseph A (2018) Prognostic gene expression assays in breast cancer: are two better than one? NPJ Breast Cancer 4:11
Centini, Ryan; Tsang, Mark; Iwata, Terri et al. (2018) Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation. PLoS One 13:e0197973
Nadaradjane, Celine; Yang, Chia-Ping Huang; Rodriguez-Gabin, Alicia et al. (2018) Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners. J Nat Prod 81:607-615
Tiwari, Sangeeta; van Tonder, Andries J; Vilchèze, Catherine et al. (2018) Arginine-deprivation-induced oxidative damage sterilizes Mycobacterium tuberculosis. Proc Natl Acad Sci U S A 115:9779-9784
Celestrin, Kevin; Díaz-Balzac, Carlos A; Tang, Leo T H et al. (2018) Four specific immunoglobulin domains in UNC-52/Perlecan function with NID-1/Nidogen during dendrite morphogenesis in Caenorhabditis elegans. Development 145:

Showing the most recent 10 out of 1508 publications