Abstract

This application is in response to NOT-OD-09-058 (NIH announces the Availability of Recovery Act Funds Competitive Revision Applications). Enhancing Roswell Park Cancer Institute (RPCI) Clinical Research Processes: Study Implementation, Participant Accrual and a Complete and Accurate Study Dataset RPCI is committed to focusing clinical research resources on processes that will improve the efficiency and effectiveness of study implementation, participant accrual and study data collection with an emphasis on investigator-initiated studies and Phase I studies. This proposal provides for an additional Clinical Research Services (CRS) staff and an Electronic Medical Record (EMR) Programmer (1.0 FTE). The EMR Programmer is needed to facilitate the EMR team in making needed changes that will improve clinical research processes to enhance accrual, prevent study protocol deviations, and enhance the collection of a complete and accurate dataset. The combination of the new CRS position and the 20% salary support for the CRS Educator who will provide consistent education for the investigators and the clinical research coordinators regarding the new EMR clinical research features will enhance the efficiency, effectiveness and accuracy of the RPCI clinical research processes: study implementation, participant accrual and accurate and complete data collection.

Public Health Relevance

The project described will be relevant to public health because it will facilitate and make more accurate the clinical research process and the study data collection process. This will allow clinical research findings to be published in a timelier manner.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA016056-33S1
Application #
7814470
Study Section
Special Emphasis Panel (ZCA1-RTRB-L (O9))
Program Officer
Ciolino, Henry P
Project Start
2009-09-30
Project End
2011-09-29
Budget Start
2009-09-30
Budget End
2011-09-29
Support Year
33
Fiscal Year
2009
Total Cost
$173,231
Indirect Cost

  Institution

Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
824771034
City
Buffalo
State
NY
Country
United States
Zip Code
14263

  Publications

Rossetti, Stefano; Wierzbicki, Andrzej J; Sacchi, Nicoletta (2018) Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer. Oncotarget 9:5016-5031
Block, Matthew S; Vierkant, Robert A; Rambau, Peter F et al. (2018) MyD88 and TLR4 Expression in Epithelial Ovarian Cancer. Mayo Clin Proc 93:307-320
Li, Qiuhui; Deng, Qu; Chao, Hsueh-Ping et al. (2018) Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses. Nat Commun 9:3600
Kawaguchi, Tstutomu; Yan, Li; Qi, Qianya et al. (2018) Novel MicroRNA-Based Risk Score Identified by Integrated Analyses to Predict Metastasis and Poor Prognosis in Breast Cancer. Ann Surg Oncol 25:4037-4046
Mett, V; Komarova, E A; Greene, K et al. (2018) Mobilan: a recombinant adenovirus carrying Toll-like receptor 5 self-activating cassette for cancer immunotherapy. Oncogene 37:439-449
Long, Mark D; Singh, Prashant K; Russell, James R et al. (2018) The miR-96 and RAR? signaling axis governs androgen signaling and prostate cancer progression. Oncogene :
Hirose, Yuki; Nagahashi, Masayuki; Katsuta, Eriko et al. (2018) Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis. Sci Rep 8:10814
Vexler, Albert; Yu, Jihnhee; Zhao, Yang et al. (2018) Expected p-values in light of an ROC curve analysis applied to optimal multiple testing procedures. Stat Methods Med Res 27:3560-3576
Mussell, Ashley L; Denson, Kayla E; Shen, He et al. (2018) Loss of KIBRA function activates EGFR signaling by inducing AREG. Oncotarget 9:29975-29984
Yendamuri, Sai; Groman, Adrienne; Miller, Austin et al. (2018) Risk and benefit of neoadjuvant therapy among patients undergoing resection for non-small-cell lung cancer. Eur J Cardiothorac Surg 53:656-663

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