Abstract

This application requests a 5 year renewal of the Cancer Center Support Grant (CCSG) for the Arizona Cancer Center (ACC). The ACC was founded in 1976, has had a CCSG since 1978, and was designated as a Comprehensive Cancer Center by the NCI in 1990. The ACC functions as a matrix center and is a division of the University of Arizona (UA) College of Medicine (COM). The goal of the cancer center is to make major contributions to research related to the basic understanding, prevention, diagnosis, treatment and control of cancer as part of the NCI's network of Cancer Centers. The major established and proposed new programs of the ACC include Molecular Carcinogenesis, Cancer Treatment, Cancer Prevention and Control, Nursing Oncology, Cancer Diagnosis, Cancer Biology, and Immunobiology. In order to support and enhance the research programs, a series of 15 core support services have either already been established previously or proposed for implementation in this CCSG application. The shared resources requested include Analytical Chemistry, Biometry, Cytogenetics, Dishwashing, Experimental Radiation, Prevention and Control, Research Pharmacy, Tissue Culture, Flow Cytometry, Clinical Research, Molecular and Computational Biology, SCID Mouse Service, Transgenic Mouse Service and Pathology Research Services.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023074-18
Application #
2087109
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1978-09-01
Project End
1998-06-30
Budget Start
1995-08-15
Budget End
1996-06-30
Support Year
18
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Arizona
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721

  Publications

Siyahian, Aida; Malik, Saad Ullah; Mushtaq, Adeela et al. (2018) Prophylaxis for Hepatitis B Virus Reactivation after Allogeneic Stem Cell Transplantation in the Era of Drug Resistance and Newer Antivirals: A Systematic Review and Meta-Analysis. Biol Blood Marrow Transplant 24:1483-1489
Stanton, Annette L; Wiley, Joshua F; Krull, Jennifer L et al. (2018) Cancer-related coping processes as predictors of depressive symptoms, trajectories, and episodes. J Consult Clin Psychol 86:820-830
Sinharay, Sanhita; Randtke, Edward A; Howison, Christine M et al. (2018) Detection of Enzyme Activity and Inhibition during Studies in Solution, In Vitro and In Vivo with CatalyCEST MRI. Mol Imaging Biol 20:240-248
Sun, Virginia; Crane, Tracy E; Slack, Samantha D et al. (2018) Rationale, development, and design of the Altering Intake, Managing Symptoms (AIMS) dietary intervention for bowel dysfunction in rectal cancer survivors. Contemp Clin Trials 68:61-66
Agasid, Mark T; Wang, Xuemin; Huang, Yiding et al. (2018) Expression, purification, and electrophysiological characterization of a recombinant, fluorescent Kir6.2 in mammalian cells. Protein Expr Purif 146:61-68
Wales, Jessica A; Chen, Cheng-Yu; Breci, Linda et al. (2018) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. J Biol Chem 293:1850-1864
Hsu, Chiu-Hsieh; Yu, Mandi (2018) Cox regression analysis with missing covariates via nonparametric multiple imputation. Stat Methods Med Res :962280218772592
Lindeman, Leila R; Randtke, Edward A; High, Rachel A et al. (2018) A comparison of exogenous and endogenous CEST MRI methods for evaluating in vivo pH. Magn Reson Med 79:2766-2772
Remeniuk, Bethany; King, Tamara; Sukhtankar, Devki et al. (2018) Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain. Pain 159:684-698
Bell, Melanie L (2018) New guidance to improve sample size calculations for trials: eliciting the target difference. Trials 19:605

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