Abstract

Purdue University is committed to the development of a multidisciplinary program for experimental cancer research with focus on the elucidation of the biological and biochemical events involved in cell transformation as the basis for new approaches to the prevention, diagnosis and chemical therapy of cancer. Ours is a specialized Cancer Center whose primary objectives are to correlate and integrate existing programs in cancer research at Purdue University, to stimulate new research in selected areas, to contribute to advanced training in cancer research, and to develop interactions among Purdue researchers, local physicians, hospitals and clinics and cancer researchers at other universities and research laboratories within the State of Indiana. This request is for a continuation of partial support for the administrative functions and the shared resources and services provided by the center as well as for center development and planning activities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023168-10
Application #
3101729
Study Section
Cancer Center Support Grant Review Committee (CCS)
Project Start
1978-04-01
Project End
1989-03-31
Budget Start
1987-04-01
Budget End
1988-03-31
Support Year
10
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Purdue University
Department
Type
Organized Research Units
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907

  Publications

Hsu, Alan Y; Gurol, Theodore; Sobreira, Tiago J P et al. (2018) Development and Characterization of an Endotoxemia Model in Zebra Fish. Front Immunol 9:607
Lin, Clement; Wu, Guanhui; Wang, Kaibo et al. (2018) Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures. Angew Chem Int Ed Engl 57:10888-10893
Xiong, Yan; Yue, Feng; Jia, Zhihao et al. (2018) A novel brown adipocyte-enriched long non-coding RNA that is required for brown adipocyte differentiation and sufficient to drive thermogenic gene program in white adipocytes. Biochim Biophys Acta Mol Cell Biol Lipids 1863:409-419
Li, Zhiguo; Kong, Yifan; Song, Longzhen et al. (2018) Plk1-Mediated Phosphorylation of TSC1 Enhances the Efficacy of Rapamycin. Cancer Res 78:2864-2875
Zhou, Wenqing; Pal, Arpita S; Hsu, Alan Yi-Hui et al. (2018) MicroRNA-223 Suppresses the Canonical NF-?B Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation. Cell Rep 22:1810-1823
Mani, Saravana Kumar Kailasam; Andrisani, Ourania (2018) Hepatitis B Virus-Associated Hepatocellular Carcinoma and Hepatic Cancer Stem Cells. Genes (Basel) 9:
Dayal, Neetu; Opoku-Temeng, Clement; Hernandez, Delmis E et al. (2018) Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines. Future Med Chem 10:823-835
Onel, Buket; Carver, Megan; Agrawal, Prashansa et al. (2018) The 3'-end region of the human PDGFR-? core promoter nuclease hypersensitive element forms a mixture of two unique end-insertion G-quadruplexes. Biochim Biophys Acta Gen Subj 1862:846-854
Sorlien, Erin L; Witucki, Mary A; Ogas, Joseph (2018) Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio. J Vis Exp :
Mani, Saravana Kumar Kailasam; Andrisani, Ourania (2018) Interferon signaling during Hepatitis B Virus (HBV) infection and HBV-associated hepatocellular carcinoma. Cytokine :

Showing the most recent 10 out of 436 publications