The Flow Cytometry (FACS) Shared Resource assists Cancer Center members in performing cell sorting and fluorescence quantification using flow cytometry. The Shared Resource consists of two flow cytometers-a Coulter Epics Elite ESP flow cytometer/cell sorter and an automated benchtop Becton Dickinson FACS Caliber flow cytometer-and a full time technician. It is supervised by Dr. Scott Lowe (Associate Professor) and Ms. Linda Rogers (Senior Research Associate), and is operated by Ms. Klara Velinzon (Research Technician). The Facility is used by a large number of Cancer Center investigators for a variety of research procedures, ranging from sorting of specific cell types within complex populations to more routine fluorescence quantification. The research assistance provided by the FACS Shared Resource is essential for the cancer research conducted in the CSHL Cancer Center, and helps to integrate our research programs. We continue to request support for fixed costs of this faculty. Because fixed, central costs are a large population of the total costs, the Cancer Center Support Grant is absolutely essential for this Shared Resource and for the research it allows.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA045508-16
Application #
6617292
Study Section
Project Start
2002-08-01
Project End
2003-07-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
16
Fiscal Year
2002
Total Cost
$78,870
Indirect Cost
Name
Cold Spring Harbor Laboratory
Department
Type
DUNS #
065968786
City
Cold Spring Harbor
State
NY
Country
United States
Zip Code
11724
Li, Jiahe; Wu, Connie; Wang, Wade et al. (2018) Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference. Proc Natl Acad Sci U S A 115:E2696-E2705
Tarumoto, Yusuke; Lu, Bin; Somerville, Tim D D et al. (2018) LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia. Mol Cell 69:1017-1027.e6
Krishnan, Navasona; Konidaris, Konstantis F; Gasser, Gilles et al. (2018) A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem 293:1517-1525
Borges, Filipe; Parent, Jean-Sébastien; van Ex, Frédéric et al. (2018) Transposon-derived small RNAs triggered by miR845 mediate genome dosage response in Arabidopsis. Nat Genet 50:186-192
Chen, Xiaoyin; Sun, Yu-Chi; Church, George M et al. (2018) Efficient in situ barcode sequencing using padlock probe-based BaristaSeq. Nucleic Acids Res 46:e22
Tonelli, Claudia; Chio, Iok In Christine; Tuveson, David A (2018) Transcriptional Regulation by Nrf2. Antioxid Redox Signal 29:1727-1745
Kumar, Vijay; Rosenbaum, Julie; Wang, Zihua et al. (2018) Partial bisulfite conversion for unique template sequencing. Nucleic Acids Res 46:e10
Lee, Je H (2018) Tracing single-cell histories. Science 359:521-522
Alexander, Joan; Kendall, Jude; McIndoo, Jean et al. (2018) Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer. Cancer Res 78:348-358
Huang, Yu-Han; Klingbeil, Olaf; He, Xue-Yan et al. (2018) POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes Dev 32:915-928

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