The Experimental Irradiation Core provides for the use of ionizing radiation for members of the University of Michigan Comprehensive Cancer Center. This facility is equipped to perform moderate dose rate gamma irradiation (0.1-4 Gy/min) of cell cultures, tissue specimens, or animals as well as low dose rate irradiation (0.05-0.5 Gy/hr) of cell cultures. The core also maintains the 137 Cs irradiator in the spf facility of the Animal Core. Personnel within the core assist in the experimental design, dosimetry, and delivery of these forms of ionizing radiation They also maintain the safety and smooth operation of this facility through routine quality assurance procedures, calibrations, and preventative maintenance. This core provides a unique opportunity for Medical Campus investigators to have this service in a convenient location, since it is the only such facility on the Medical Campus. The specific goals of the Irradiation Core are to: Support studies in the radiation biology of moderate dose rate irradiation of cell cultures and small animals, such as mice, rats, and rabbits. Permit the study of low dose rate irradiation in cell culture. Provide irradiation services for investigators whose primary interests are not in radiation biology, but who need this tool in support of other efforts (for example, immunosuppression of animals prior to stem cell transplantation through total body irradiation).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA046592-15
Application #
6597022
Study Section
Project Start
2002-06-01
Project End
2003-05-31
Budget Start
Budget End
Support Year
15
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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