? OVERALL The Robert H. Lurie Comprehensive Cancer Center of Northwestern University is an NCI-designated, comprehensive matrix cancer center conducting a broad range of multidisciplinary clinical, basic, translational and population science research. The Lurie Cancer Center integrates the expertise and resources of the Feinberg School of Medicine (Chicago Campus) and its affiliated hospitals along with those of departments located on the University's Evanston Campus. The Lurie Cancer Center brings together 271 members from 31 Departments in 4 Schools. Established in 1974, the Lurie Cancer Center has been dedicated to the process of discovery, advancing medical knowledge and providing compassionate, patient-centered state-of-the-art cancer care, and conducting community outreach and survivorship programs. This is reflected in the following goals: 1. To conduct and support innovative basic, translational, clinical, and cancer prevention and control focused cancer research throughout the University. 2. To coordinate and integrate cancer-related activities, including community outreach initiatives. 3. To develop and conduct cancer education programs 4. To promote state-of-the-art cancer care at NU affiliated hospitals and drive precision cancer medicine initiatives. These goals are accomplished through the activities of 8 established programs and 14 shared resources: Over the current CCSG funding period there has been renewed institutional support and investment, new leadership, and significant growth in all divisions and programs of the LCC. Over the last funding period 88 new faculty have been recruited, including 30 clinical investigators and 58 laboratory or population scientists. There has been strengthened clinical and translational leadership and infrastructure and enhanced cancer focus. By leveraging the new Institutional commitment and support and significant philanthropic resources, the LCC will continue to develop innovative approaches to reduce the cancer burden in our catchment area and nationwide.

Public Health Relevance

This Cancer Center Support Grant is requested to provide support for the critical infrastructure and shared resources needed by Lurie Cancer Center investigators to develop approaches and methods for cancer prevention, treatment and control.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA060553-26
Application #
9982805
Study Section
Special Emphasis Panel (ZCA1)
Program Officer
Ptak, Krzysztof
Project Start
1997-08-15
Project End
2023-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
26
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Fisher, Daniel W; Han, Ye; Lyman, Kyle A et al. (2018) HCN channels in the hippocampus regulate active coping behavior. J Neurochem 146:753-766
Sullivan, David P; Bui, Triet; Muller, William A et al. (2018) In vivo imaging reveals unique neutrophil transendothelial migration patterns in inflamed intestines. Mucosal Immunol 11:1571-1581
Russi, Abigail E; Ebel, Mark E; Yang, Yuchen et al. (2018) Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility. Proc Natl Acad Sci U S A 115:E1520-E1529
Frankowski, Kevin J; Wang, Chen; Patnaik, Samarjit et al. (2018) Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10:
Melo-Cardenas, Johanna; Xu, Yuanming; Wei, Juncheng et al. (2018) USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism. Blood 132:423-434
Sato, Tatsuya; Chang, Hsiang-Chun; Bayeva, Marina et al. (2018) mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function. Proc Natl Acad Sci U S A 115:E6291-E6300
Wiwatpanit, Teerawat; Lorenzen, Sarah M; Cantú, Jorge A et al. (2018) Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature 563:691-695
Spring, Bonnie; Pellegrini, Christine; McFadden, H G et al. (2018) Multicomponent mHealth Intervention for Large, Sustained Change in Multiple Diet and Activity Risk Behaviors: The Make Better Choices 2 Randomized Controlled Trial. J Med Internet Res 20:e10528
Buglak, Nicholas E; Jiang, Wulin; Bahnson, Edward S M (2018) Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats. Redox Biol 19:166-178
Yang, Ruiguo; Lemaître, Vincent; Huang, Changjin et al. (2018) Monoclonal Cell Line Generation and CRISPR/Cas9 Manipulation via Single-Cell Electroporation. Small 14:e1702495

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