- Biostatistics Shared Resource (BSR) The overarching goal of the Biostatistics Shared Resource (BSR) within the Chao Family Comprehensive Cancer Center (CFCCC) is to provide statistical and intellectual support to all CFCCC investigators at all phases of scientific projects. The mission of the BSR faculty and staff is to be intimately involved in the conception, design, implementation, analysis, and reporting of research conducted by members of the CFCCC. While the majority of effort from BSR faculty is devoted to providing collaboration and service to CFCCC investigators the BSR also encourages the development of statistical methodologic research that relates directly to the scientific agenda and needs of CFCCC investigators. The BSR is staffed by six PhD level statisticians and one MS level statistician. Dr. Daniel Gillen, Professor of Statistics with affiliate appointments in the Department of Epidemiology and the Program in Public Health, serves as the Director of the BSR. Dr. Michael Phelan serves as the BSR Facilities Manager. Drs. Christine McLaren, Kathryn Osann, Thomas Taylor, and Chad Garner all hold faculty appointments at UC Irvine. The faculty and staff of the BSR have particular expertise in multiple areas of statistical methodology with applications to cancer research, making them an invaluable resource for CFCCC members and key contributors to the overall research mission of the Cancer Center. Examples of the many services provided by the BSR include collaboration on study design, data analysis, and interpretation, development of research protocols and grant proposals, assistance with database design and linkage of clinical, epidemiologic, and laboratory data, statistical expertise for CFCCC oversight committees, and education, training, and mentoring of CFCCC members.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA062203-23
Application #
9851362
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2020-02-01
Budget End
2021-01-31
Support Year
23
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Type
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92617
Yu, James; Landberg, Jenny; Shavarebi, Farbod et al. (2018) Bioengineering triacetic acid lactone production in Yarrowia lipolytica for pogostone synthesis. Biotechnol Bioeng 115:2383-2388
Oliver, Andrew; Kay, Matthew; Cooper, Kerry K (2018) Comparative genomics of cocci-shaped Sporosarcina strains with diverse spatial isolation. BMC Genomics 19:310
Mahlbacher, Grace; Curtis, Louis T; Lowengrub, John et al. (2018) Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment. J Immunother Cancer 6:10
Neek, Medea; Tucker, Jo Anne; Kim, Tae Il et al. (2018) Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. Biomaterials 156:194-203
McLelland, Bryce T; Lin, Bin; Mathur, Anuradha et al. (2018) Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats. Invest Ophthalmol Vis Sci 59:2586-2603
Bota, Daniela A; Chung, Jinah; Dandekar, Manisha et al. (2018) Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4+ T-lymphocyte counts. CNS Oncol 7:CNS22
Han, Han; Qi, Ruxi; Zhou, Jeff Jiajing et al. (2018) Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction. Mol Cell 72:328-340.e8
Solares, Edwin A; Chakraborty, Mahul; Miller, Danny E et al. (2018) Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing. G3 (Bethesda) 8:3143-3154
Wang, Yajun; Ngor, Arlene K; Nikoomanzar, Ali et al. (2018) Evolution of a General RNA-Cleaving FANA Enzyme. Nat Commun 9:5067
Qiu, Xiaolong; Lombardo, Jeremy A; Westerhof, Trisha M et al. (2018) Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab Chip 18:2776-2786

Showing the most recent 10 out of 1106 publications