The Diabetes Research Center has as its major research objectives multidisciplinary investigations of the pathogenesis of diabetes mellitus and its complications with the long-term goal of developing and evaluating new therapeutic approaches to these problems. The Diabetes Research Center program is designed (1) to facilitate and encourage the development of new interdisciplinary research programs and the involvement of established investigators not previously active in this field, (2) to assist the development of younger faculty members with primary training in diverse clinical and basic sciences who devote themselves to careers in diabetes mellitus related research, (3) to assist in the recruitment of new investigators to fill identified deficits in the overall research program, (4) to provide coordination of the planning and execution of the overall research program in diabetes, and of its related educational and research training programs, (5) to provide core support for the Diabetes Research Center research program through the provision of core facilities and services, (6) to provide an efficient mechanism for the development and evaluation of new research initiatives and support of pilot projects of high scientific merit, (7) to provide a means for evaluating the quality of the overall research program to insure its continued productivity, and (8) to provide a means for the dissemination of new information.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK019525-12
Application #
3101938
Study Section
(SRC)
Project Start
1977-03-01
Project End
1991-02-28
Budget Start
1988-03-01
Budget End
1989-02-28
Support Year
12
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Rickels, M R; Markmann, E; Naji, A (2018) Successful pregnancies after islet transplantation for type 1 diabetes. Am J Transplant :
Friedman, Elliot S; Li, Yun; Shen, Ting-Chin David et al. (2018) FXR-Dependent Modulation of the Human Small Intestinal Microbiome by the Bile Acid Derivative Obeticholic Acid. Gastroenterology 155:1741-1752.e5
Rickels, Michael R; DuBose, Stephanie N; Toschi, Elena et al. (2018) Mini-Dose Glucagon as a Novel Approach to Prevent Exercise-Induced Hypoglycemia in Type 1 Diabetes. Diabetes Care 41:1909-1916
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Kim, Boa; Jang, Cholsoon; Dharaneeswaran, Harita et al. (2018) Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest 128:4543-4556

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