The goal of the RIA Core facility is to perform accurate and cost-effective analysis of hormones and analytes for NIH-funded users at the University of Pennsylvania, and neighboring institutions. In the 1996-2001 funding periods, under the leadership of Drs. Bryan Wolf and Heather Collins, the RIA Core has evolved from a facility that focused on rat and human insulin, glucagon and C-peptide (52,000 samples per year) to a diverse, high-volume and cost-effective service. In 2001, nearly 96,000 samples will have been assayed by RIA, EIA, ELISA for over 13 analytes which include rat/mouse insulin, dog insulin, monkey insulin, human insulin, rat and human glucagon, human C-peptide, rat and human leptin, rat corticosterone, human salivary and serum cortisol, CAMP, ACTH, T4. We utilize a charge-back system to recover the cost of the assays and our charges vary from $0.50 to $3.50 per sample, which are among the lowest of all DERC/DRTCs. Over 20 NIH-funded investigators have used our services and we have facilitated the research of junior as well as senior investigators.
| Wooldridge, Amy L; Bischof, Robert J; Liu, Hong et al. (2018) Late-gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR. Am J Physiol Regul Integr Comp Physiol 314:R22-R33 |
| Kim, Boa; Jang, Cholsoon; Dharaneeswaran, Harita et al. (2018) Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest 128:4543-4556 |
| Gibson, Christopher E; Boodhansingh, Kara E; Li, Changhong et al. (2018) Congenital Hyperinsulinism in Infants with Turner Syndrome: Possible Association with Monosomy X and KDM6A Haploinsufficiency. Horm Res Paediatr 89:413-422 |
| Hill, David A; Lim, Hee-Woong; Kim, Yong Hoon et al. (2018) Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue. Proc Natl Acad Sci U S A 115:E5096-E5105 |
| Kim, Yong Hoon; Marhon, Sajid A; Zhang, Yuxiang et al. (2018) Rev-erb? dynamically modulates chromatin looping to control circadian gene transcription. Science 359:1274-1277 |
| Mowel, Walter K; Kotzin, Jonathan J; McCright, Sam J et al. (2018) Control of Immune Cell Homeostasis and Function by lncRNAs. Trends Immunol 39:55-69 |
| Rickels, Michael R; Peleckis, Amy J; Dalton-Bakes, Cornelia et al. (2018) Continuous Glucose Monitoring for Hypoglycemia Avoidance and Glucose Counterregulation in Long-Standing Type 1 Diabetes. J Clin Endocrinol Metab 103:105-114 |
| Guan, Dongyin; Xiong, Ying; Borck, Patricia C et al. (2018) Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell 174:831-842.e12 |
| Jang, Cholsoon; Chen, Li; Rabinowitz, Joshua D (2018) Metabolomics and Isotope Tracing. Cell 173:822-837 |
| Shoshkes-Carmel, Michal; Wang, Yue J; Wangensteen, Kirk J et al. (2018) Subepithelial telocytes are an important source of Wnts that supports intestinal crypts. Nature 557:242-246 |
Showing the most recent 10 out of 720 publications
