(Taken directly from the application) This is a competitive renewal of the New York Obesity Research Center (NYORC). The NYORC integrates the obesity research programs situated at the St. Luke's-Roosevelt Center and New York Presbyterian Hospital Center of Columbia University, Cornell Medical College, and the University of Vermont. The objectives of the combined center include the following: (i) to bring together, under the Center's aegis, a critical mass of independent investigators of separately funded research projects who share a strong interest in the study of obesity-related problems; (ii) to manage the pilot and feasibility (P/F) program and the program enrichment activities to promote and test new research ideas, stimulate productivity, foster the development of talented new investigators in the field, and persuade creative scientists working in areas or disciplines not ordinarily concerned with obesity to become involved in obesity-related research; (iii) to provide participating investigators of funded projects relevant to obesity research with valuable laboratory, technical and educational services that otherwise would not be available, thereby improving the productivity and efficiency of their operations; and (iv) to maintain a dynamic focus for obesity-related investigation, so as to move the field more effectively into basic and applied research critical to the solution of key problems. Seven Cores offer a comprehensive spectrum of services: funding is requested for 6 of them in this application; (i) the Administrative Core, which provides a structure for peer evaluation of P/F protocols, training initiatives, a Sub-Core for Biostatistical/Computational services and an enrichment program; (ii) a Body Composition/Energy Expenditure Core (iii) a Hormone/Metabolite and Mass Spectrometry Core; (iv) a Molecular Biology/Molecular Genetics Core: and (v) an Ingestive Behavior Core. No funding is requested for the other two cores, (vi) an In-Patient General Clinical Research Center Core for conduct of rigorously controlled metabolic studies, located at both St. Luke's-Roosevelt and New York Presbyterian, and (vii) an Out-patient Core for clinical investigation of obesity at St. Luke's-Roosevelt.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK026687-25
Application #
6855092
Study Section
Special Emphasis Panel (ZDK1-GRB-1 (M1))
Program Officer
Miles, Carolyn
Project Start
1980-12-01
Project End
2005-11-30
Budget Start
2004-12-01
Budget End
2005-11-30
Support Year
25
Fiscal Year
2005
Total Cost
$1,021,000
Indirect Cost
Name
St. Luke's-Roosevelt Institute for Health Sciences
Department
Type
DUNS #
623216371
City
New York
State
NY
Country
United States
Zip Code
10019
Heymsfield, S B; Peterson, C M; Bourgeois, B et al. (2018) Human energy expenditure: advances in organ-tissue prediction models. Obes Rev 19:1177-1188
Shah, Ankit; Levesque, Kiarra; Pierini, Esmeralda et al. (2018) Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery. Diabetes Obes Metab 20:1018-1023
Hayden, Kathleen M; Baker, Laura D; Bray, George et al. (2018) Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study. Alzheimers Dement (Amst) 10:41-48
Shechter, Ari; Schwartz, Gary J (2018) Gut-brain nutrient sensing in food reward. Appetite 122:32-35
Rosenbaum, Michael; Leibel, Rudolph L (2018) Physiological responses to leptin levels in lipodystrophy: a model for other hypoleptinemias? J Clin Invest 128:3237-3239
Toledo, Miriam; Batista-Gonzalez, Ana; Merheb, Emilio et al. (2018) Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1. Cell Metab 28:268-281.e4
Pizinger, Theresa; Kovtun, Kyle; RoyChoudhury, Arindam et al. (2018) Pilot study of sleep and meal timing effects, independent of sleep duration and food intake, on insulin sensitivity in healthy individuals. Sleep Health 4:33-39
Kissileff, H R; Herzog, M (2018) Progressive ratio (PR) schedules and the sipometer: Do they measure wanting, liking, and/or reward? A tribute to Anthony Sclafani and Karen Ackroff. Appetite 122:44-50
Pan, Xiaoyue; Schwartz, Gary J; Hussain, M Mahmood (2018) Oleoylethanolamide differentially regulates glycerolipid synthesis and lipoprotein secretion in intestine and liver. J Lipid Res 59:2349-2359
Davidson, Lance E; Yu, Wen; Goodpaster, Bret H et al. (2018) Fat-Free Mass and Skeletal Muscle Mass Five Years After Bariatric Surgery. Obesity (Silver Spring) 26:1130-1136

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