Abstract

The Liver Core Center will provide technical and intellectual support and expertise for the liver-related research projects in the Schools of Medicine and Pharmacy of the University of California, San Francisco. It further will provide limited funds for pilot and feasibility studies. The Center will be based on the combined facilities and resources of the Schools of Medicine and Pharmacy, the Moffitt-University Hospital, the San Francisco Veterans Administration Hospital and the San Francisco General Hospital. The overall goals of the Center are to enhance the quality and productivity of individually funded research projects; to foster interdisciplinary communication and collaboration between investigators of different departments and schools; to stimulate new interdisciplinary research projects; to provide technical and procedural resources not available to individual research projects; to optimize the use of available technical and intellectual resources. The main emphasis of the Core Center will be on new and novel concepts and approaches to liver function and structure, both in the physiological state and in a variety of diseases, including drug-induced liver injury. The Core Center will be under the direction of a Program Director, two Deputy Directors, an Executive Committee and an Advisory Board, responsible to the Dean of the School of Medicine.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK026743-10
Application #
3101986
Study Section
(SRC)
Project Start
1985-07-01
Project End
1990-11-30
Budget Start
1989-07-01
Budget End
1990-11-30
Support Year
10
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Sarkar, Monika; Terrault, Norah; Duwaerts, Caroline C et al. (2018) The Association of Hispanic Ethnicity with Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome. Curr Opin Gynecol Obstet 1:24-33
Benet, Leslie Z; Bowman, Christine M; Liu, Shufang et al. (2018) The Extended Clearance Concept Following Oral and Intravenous Dosing: Theory and Critical Analyses. Pharm Res 35:242
Verstraete, Sofia G; Wojcicki, Janet M; Perito, Emily R et al. (2018) Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010. Environ Health 17:12
Dave, S; Dodge, J L; Terrault, N A et al. (2018) Racial and Ethnic Differences in Graft Loss Among Female Liver Transplant Recipients. Transplant Proc 50:1413-1423
Maher, Jacquelyn J (2018) Macrophages Steal STING From the Infectious Disease Playbook to Promote Nonalcoholic Fatty Liver Disease. Gastroenterology 155:1687-1688
Cullaro, Giuseppe; Park, Meyeon; Lai, Jennifer C (2018) ""Normal"" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis. Hepatology 68:1953-1960
Lee, Brian P; Mehta, Neil; Platt, Laura et al. (2018) Outcomes of Early Liver Transplantation for Patients With Severe Alcoholic Hepatitis. Gastroenterology 155:422-430.e1
Campos-Varela, Isabel; Agudelo, Eliana Z; Sarkar, Monika et al. (2018) Use of a hepatitis C virus (HCV) RNA-positive donor in a treated HCV RNA-negative liver transplant recipient. Transpl Infect Dis 20:
Dong, Mingjie; Liu, Xianqiong; Evert, Katja et al. (2018) Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. Cell Death Dis 9:31
Perito, Emily R; Bucuvalas, John; Lai, Jennifer C (2018) Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates. Am J Transplant :

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