Abstract

The mission ofthe Center for Gastrointestinal Biology and Disease is to promote and enhance multidisciplinary digestive disease research. The center achieves this purpose through: ? Core laboratories that provide training, technical support, laboratory animals, reagents, and/or assays, ? A pilot/feasibility program that offers startup funds to junior investigators, or to established investigators who wish to pursue new directions in research, ? A scientific enrichment program.-- consisting of seminars, lectures by visiting scientists, workshops and research competitions for trainees ~ that improves the intellectual climate for gastrointestinal biological research, and promotes cooperation, collaboration and communication among involved personnel, and ? A professional development and training program that promotes the development of junior faculty and trainees.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034987-28
Application #
8385559
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
28
Fiscal Year
2013
Total Cost
$566,158
Indirect Cost
$129,427

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Li, Feng; Kakoki, Masao; Smid, Marcela et al. (2018) Causative Effects of Genetically Determined High Maternal/Fetal Endothelin-1 on Preeclampsia-Like Conditions in Mice. Hypertension 71:894-903
Rogala, Allison R; Schoenborn, Alexi A; Fee, Brian E et al. (2018) Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. Dis Model Mech 11:
Ho, G-T; Aird, R E; Liu, B et al. (2018) MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. Mucosal Immunol 11:120-130
Yan, Jing; Takakura, Ayumi; Zandi-Nejad, Kambiz et al. (2018) Mechanisms of gut microbiota-mediated bone remodeling. Gut Microbes 9:84-92
Peery, Anne F; Shaheen, Nicholas J; Cools, Katherine S et al. (2018) Morbidity and mortality after surgery for nonmalignant colorectal polyps. Gastrointest Endosc 87:243-250.e2
Mazzone, C M; Pati, D; Michaelides, M et al. (2018) Acute engagement of Gq-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior. Mol Psychiatry 23:143-153
Rolston, Vineet S; Boroujerdi, Laleh; Long, Millie D et al. (2018) The Influence of Hormonal Fluctuation on Inflammatory Bowel Disease Symptom Severity-A Cross-Sectional Cohort Study. Inflamm Bowel Dis 24:387-393
Eaton, Kathryn; Pirani, Ali; Snitkin, Evan S et al. (2018) Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota. Elife 7:
Dong, Jing; Levine, David M; Buas, Matthew F et al. (2018) Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Clin Gastroenterol Hepatol 16:1598-1606.e4
Truax, Agnieszka D; Chen, Liang; Tam, Jason W et al. (2018) The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. Cell Host Microbe 24:364-378.e6

Showing the most recent 10 out of 944 publications