ENRICHMENT PROGRAM: ABSTRACT The DRC Enrichment Program has fostered the exchange and discussion of diabetes-related research information for more than 30 years, not only within the Joslin Diabetes Center but also with external scientists with similar interests. The program has several major components: (1) the Longwood Area Diabetes/Metabolism Research Seminar Series, consisting of weekly research seminars featuring invited outside experts, including five named lectures per year that recognize speakers with particularly high-level accomplishments in the diabetes-related scientific community, (2) the weekly Internal Research Seminar Series, a platform for faculty investigators, senior postdoctoral research fellows, and graduate students at Joslin to share their ongoing research, (3) the Clinical Seminar Series, which includes clinical diabetes and obesity-related seminars, case presentations, and journal club presentations, (4) the Summer Seminar Series, which highlights services provided by each DRC Core and introduces new technologies that may enhance current research, (5) special seminars throughout the year, (6) a two-day Research Retreat, held every two years to foster interactions and the exchange of ideas among Joslin researchers, (7) an Annual Poster Day to facilitate informal interactions and data discussion between lab groups, and (8) the Joslin Summer Research Student Program Lecture Series, given by Joslin investigators to undergraduate and medical students within our summer programs, which provides a background of both type 1 and type 2 diabetes as well as diabetes- related research inside and outside the Joslin. Within this framework, over 500 lectures and seminars have been held during the past funding period on topics ranging from basic research to clinical science, including five annual named lectures (the Alexander Marble Lecture on Diabetes, the Ray A. and Robert L. Kroc Lecture, the Priscilla White Annual Lecture on Metabolism, the Michael Brownlee Lectureship in Diabetes Research, and the newly-inaugurated C. Ronald Kahn Distinguished Lectureship). The Enrichment Program is unique in that every member of the Joslin participates, from basic scientists to practicing physicians, including all backgrounds and levels of training, from the newest Joslin trainees and Harvard medical students to emeritus professors. Because the Enrichment Program attracts such a wide array of renowned scientists, it truly enhances all clinical and research programs at the Joslin and the overall strength of the DRC, providing a constant flow and exchange of ideas through the center that is critical for the functioning and enhancement of growth of every core and section. Moreover, seminars supported by the Enrichment Program also provide a focus for diabetes and metabolism-related activity and interactions throughout the Longwood Medical Area and the broader Boston medical community.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
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Special Emphasis Panel (ZDK1)
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Joslin Diabetes Center
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Rabiee, Atefeh; Krüger, Marcus; Ardenkjær-Larsen, Jacob et al. (2018) Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action. Cell Signal 47:1-15
Cai, Weikang; Xue, Chang; Sakaguchi, Masaji et al. (2018) Insulin regulates astrocyte gliotransmission and modulates behavior. J Clin Invest 128:2914-2926
Nowak, Natalia; Skupien, Jan; Smiles, Adam M et al. (2018) Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development. Kidney Int 93:1198-1206
Aguayo-Mazzucato, Cristina; Lee Jr, Terence B; Matzko, Michelle et al. (2018) T3 Induces Both Markers of Maturation and Aging in Pancreatic ?-Cells. Diabetes 67:1322-1331
Bartelt, Alexander; Widenmaier, Scott B; Schlein, Christian et al. (2018) Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. Nat Med 24:292-303
Fujisaka, Shiho; Avila-Pacheco, Julian; Soto, Marion et al. (2018) Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites. Cell Rep 22:3072-3086
Van Name, Michelle A; Hilliard, Marisa E; Boyle, Claire T et al. (2018) Nighttime is the worst time: Parental fear of hypoglycemia in young children with type 1 diabetes. Pediatr Diabetes 19:114-120
Weisman, Alanna; Lovblom, Leif E; Keenan, Hillary A et al. (2018) Diabetes Care Disparities in Long-standing Type 1 Diabetes in Canada and the U.S.: A Cross-sectional Comparison. Diabetes Care 41:88-95
Panduro, Marisella; Benoist, Christophe; Mathis, Diane (2018) Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A 115:E2585-E2593
McGill, Dayna E; Volkening, Lisa K; Pober, David M et al. (2018) Depressive Symptoms at Critical Times in Youth With Type 1 Diabetes: Following Type 1 Diabetes Diagnosis and Insulin Pump Initiation. J Adolesc Health 62:219-225

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