The Administrative Core is the central command and operations post of the Liver Pathobiology and Gene Therapy Research Core Center. The Core maintains and manages the fundamental infrastructure necessary to sustain and strengthen basic translational and clinical liver-related research at the Center. All planning, communications and activities of the Center go through this office. Dr. Allan W. Wolkoff, Director of the Center is Director of the Administrative Core. He is assisted by the Associate Director, David A. Shafritz, who oversees operation of the Research Core Facilities and our Administrator, who manages the Core Center grant and grants submitted by Center Investigators. She assists in preparation of all budgets and personnel assigned to grants flowing through the Center;in addition, she manages expenditures by the Core Facilities, Pilot and Feasibility Studies and the Enrichment Program. Four key committees, 1) the Executive Committee, 2) the Scientific Advisory Committee, 3) the Core Facilities Management Committee and the 4) Educational and Enrichment Committee work to ensure smooth operations of the Center and assure outstanding program management and effective operation. Working together, under the outstanding vision and leadership of the Director, and with continued support from NIDDK, Albert Einstein College of Medicine and Montefiore Medical Center, the Pathobiology and Gene Therapy Research Core Center enthusiastically looks forward to achieving major advances in liver pathobiology and treatment of liver diseases, during the next funding period.

Public Health Relevance

It is estimated that over 30 million Americans have a liver disorder;further, liver disease is one of the ten leading causes of death in the United States. Although advances have been made in diagnosis and treatment of liver diseases, there is still much to be learned. The Liver Research Center at Einstein provides a multidisciplinary approach to the study of liver disease by integrating basic and clinical research efforts to foster development of new insights and paradigms.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK041296-26
Application #
8743562
Study Section
Special Emphasis Panel (ZDK1-GRB-8 (J2))
Project Start
2014-08-15
Project End
2019-06-30
Budget Start
2014-08-15
Budget End
2015-06-30
Support Year
26
Fiscal Year
2014
Total Cost
$632,126
Indirect Cost
$253,608
Name
Albert Einstein College of Medicine
Department
Type
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Dulyaninova, Natalya G; Ruiz, Penelope D; Gamble, Matthew J et al. (2018) S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms. Mol Biol Cell 29:632-642
Kakabadze, Zurab; Kakabadze, Ann; Chakhunashvili, David et al. (2018) Decellularized human placenta supports hepatic tissue and allows rescue in acute liver failure. Hepatology 67:1956-1969
Rao, Lu; Hülsemann, Maren; Gennerich, Arne (2018) Combining Structure-Function and Single-Molecule Studies on Cytoplasmic Dynein. Methods Mol Biol 1665:53-89
Gong, Zhenwei; Tasset, Inmaculada; Diaz, Antonio et al. (2018) Humanin is an endogenous activator of chaperone-mediated autophagy. J Cell Biol 217:635-647
Kale, Abhijit; Ji, Zhejun; Kiparaki, Marianthi et al. (2018) Ribosomal Protein S12e Has a Distinct Function in Cell Competition. Dev Cell 44:42-55.e4
Caballero, Benjamin; Wang, Yipeng; Diaz, Antonio et al. (2018) Interplay of pathogenic forms of human tau with different autophagic pathways. Aging Cell 17:
Akiyama, Matthew J; Agyemang, Linda; Arnsten, Julia H et al. (2018) Rationale, design, and methodology of a trial evaluating three models of care for HCV treatment among injection drug users on opioid agonist therapy. BMC Infect Dis 18:74
Willis, Ian M (2018) Maf1 phenotypes and cell physiology. Biochim Biophys Acta Gene Regul Mech 1861:330-337
Wang, Tony Y; Portincasa, Piero; Liu, Min et al. (2018) Mouse models of gallstone disease. Curr Opin Gastroenterol 34:59-70
Hodge, Dayle Q; Cui, Jihong; Gamble, Matthew J et al. (2018) Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition. Sci Rep 8:841

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