The goal of the Pilot and Feasibility Program of the DERC will encourage investigators to pursue and develop critical scientific questions in diabetes. Towards this goal, the DERC provides research funds to new investigators for scientific studies related to the field of diabetes and/or endocrinology. The funding mechanism is also available to senior investigators whose research has not focused towards diabetes, its pathogenesis ore complications, who wish to expand their research field and focus some of their research skills on diabetes. The awarding of pilot and feasibility grants is based upon the scientific merit of the investigator's proposal as evaluated by the DERC Pilot and Feasibility Committee chaired by Dr. Tony McCall, and importantly by scientists outside of the University with recognized expertise in the relevant field. It is the expectation of the DERC that the successful applicants will produce and publish data stemming from the studies supported by the DERC. The Pilot and Feasibility Committee evaluates progress on the studies after the first six months of funding with the aim of assisting the investigators in accomplishing their goals by constructive advice and consultation. Furthermore, we encourage pilot and feasibility awardees to continue their studies by applying for extemal funding for the project once preliminary data has been gathered.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK063609-04
Application #
7550812
Study Section
Special Emphasis Panel (ZDK1)
Project Start
2006-02-01
Project End
2008-01-31
Budget Start
2006-02-01
Budget End
2007-01-31
Support Year
4
Fiscal Year
2006
Total Cost
$296,000
Indirect Cost
Name
University of Virginia
Department
Type
DUNS #
065391526
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
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Kim, Hyun Bae; Kumar, Anil; Wang, Lifu et al. (2010) Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. Mol Cell Biol 30:3126-39
Roland, Alison V; Nunemaker, Craig S; Keller, Susanna R et al. (2010) Prenatal androgen exposure programs metabolic dysfunction in female mice. J Endocrinol 207:213-23
Johnson, Michael L; Veldhuis, Paula P; Grimmichova, Tereza et al. (2010) Validation of a deconvolution procedure (AutoDecon) for identification and characterization of fasting insulin secretory bursts. J Diabetes Sci Technol 4:1205-13
Crim, William S; Wu, Runpei; Carter, Jeffrey D et al. (2010) AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. Mol Cell Endocrinol 323:246-55
Guimont-Desrochers, Fanny; Cappello, Zachary John; Chagnon, Miguel et al. (2009) Cutting edge: genetic characterization of IFN-producing killer dendritic cells. J Immunol 182:5193-7

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