The goal of the MNORC is to support, facilitate, enhance and guide Research Base investigators in their quest for important new information related to nutrition, obesity and related metabolic disorders. In order to support an integrative, 'team science'approach to biomedical research, the breadth of scientific talent that needs to be attracted to a Center, such as the MNORC, will necessarily need expansion. Since the inception of the Michigan Metabolomics and Obesity Center (MMOC) in 2006, a focus has been on attracting the interest of a broad range of scientists, not only those who have a focused interest in nutrition and obesity, but also those investigators who have skills in complementary areas, who can bring their considerable talents to the study of nutrition and obesity. These latter scientists have brought new thinking in metabolomics, microfluidics, imaging, cognitive sciences and informatics that have enriched seminars, symposia, retreats and, most importantly, research programs. The MNORC leadership is committed to an inclusive policy to expand the thinking of investigators and further scientific team building.

Public Health Relevance

Obesity has become a national problem that has defied easy treatment. The Michigan Nutrition Obesity Research Center will provide researchers the opportunity to utilize advanced technologies and computational tools to understand how causes of obesity vary among individuals and across the population. Through these efforts, health professionals will be able to translate these lessons to the design and implementation of novel dietary, exercise and medication interventions to control obesity and obesity-related diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK089503-03
Application #
8290531
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (M2))
Program Officer
Evans, Mary
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
3
Fiscal Year
2012
Total Cost
$1,166,250
Indirect Cost
$416,250
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Horowitz, Jeffrey F; Ortega, Juan F; Hinko, Alexander et al. (2018) Changes in markers for cardio-metabolic disease risk after only 1-2 weeks of a high saturated fat diet in overweight adults. PLoS One 13:e0198372
Peck, Bailey C E; Seeley, Randy J (2018) How does 'metabolic surgery' work its magic? New evidence for gut microbiota. Curr Opin Endocrinol Diabetes Obes 25:81-86
Isaman, Deanna J M; Rothberg, Amy E; Herman, William H (2018) The Effect of Attrition on Reported Diabetes Remission Rates Following Roux-en-Y Gastric Bypass: a Sensitivity Analysis. Obes Surg 28:1308-1312
Meng, Zhuo-Xian; Tao, Weiwei; Sun, Jingxia et al. (2018) Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle. Diabetes 67:85-97
Ward, Kristen M; Yeoman, Larisa; McHugh, Cora et al. (2018) Atypical Antipsychotic Exposure May Not Differentiate Metabolic Phenotypes of Patients with Schizophrenia. Pharmacotherapy 38:638-650
Tang, Ming; Gao, Chao; Goutman, Stephen A et al. (2018) Model-Based and Model-Free Techniques for Amyotrophic Lateral Sclerosis Diagnostic Prediction and Patient Clustering. Neuroinformatics :
Bagchi, Devika P; Forss, Isabel; Mandrup, Susanne et al. (2018) SnapShot: Niche Determines Adipocyte Character II. Cell Metab 27:266-266.e1
Arble, Deanna M; Evers, Simon S; Bozadjieva, Nadejda et al. (2018) Metabolic comparison of one-anastomosis gastric bypass, single-anastomosis duodenal-switch, Roux-en-Y gastric bypass, and vertical sleeve gastrectomy in rat. Surg Obes Relat Dis 14:1857-1867
Callaghan, Brian C; Xia, Rong; Reynolds, Evan et al. (2018) Better diagnostic accuracy of neuropathy in obesity: A new challenge for neurologists. Clin Neurophysiol 129:654-662
Zeng, Lixia; Mathew, Anna V; Byun, Jaeman et al. (2018) Myeloperoxidase-derived oxidants damage artery wall proteins in an animal model of chronic kidney disease-accelerated atherosclerosis. J Biol Chem 293:7238-7249

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