The goal of the MNORC is to support, facilitate, enhance and guide Research Base investigators in their quest for important new information related to nutrition, obesity and related metabolic disorders. In order to support an integrative, 'team science'approach to biomedical research, the breadth of scientific talent that needs to be attracted to a Center, such as the MNORC, will necessarily need expansion. Since the inception of the Michigan Metabolomics and Obesity Center (MMOC) in 2006, a focus has been on attracting the interest of a broad range of scientists, not only those who have a focused interest in nutrition and obesity, but also those investigators who have skills in complementary areas, who can bring their considerable talents to the study of nutrition and obesity. These latter scientists have brought new thinking in metabolomics, microfluidics, imaging, cognitive sciences and informatics that have enriched seminars, symposia, retreats and, most importantly, research programs. The MNORC leadership is committed to an inclusive policy to expand the thinking of investigators and further scientific team building.

Public Health Relevance

Obesity has become a national problem that has defied easy treatment. The Michigan Nutrition Obesity Research Center will provide researchers the opportunity to utilize advanced technologies and computational tools to understand how causes of obesity vary among individuals and across the population. Through these efforts, health professionals will be able to translate these lessons to the design and implementation of novel dietary, exercise and medication interventions to control obesity and obesity-related diseases.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (M2))
Program Officer
Evans, Mary
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Michigan Ann Arbor
Internal Medicine/Medicine
Schools of Medicine
Ann Arbor
United States
Zip Code
Callaghan, Brian C; Xia, Rong; Reynolds, Evan et al. (2018) Better diagnostic accuracy of neuropathy in obesity: A new challenge for neurologists. Clin Neurophysiol 129:654-662
Zeng, Lixia; Mathew, Anna V; Byun, Jaeman et al. (2018) Myeloperoxidase-derived oxidants damage artery wall proteins in an animal model of chronic kidney disease-accelerated atherosclerosis. J Biol Chem 293:7238-7249
Rumora, Amy E; Lentz, Stephen I; Hinder, Lucy M et al. (2018) Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons. FASEB J 32:195-207
Hussain, Iram; Patni, Nivedita; Ueda, Masako et al. (2018) A Novel Generalized Lipodystrophy-Associated Progeroid Syndrome Due to Recurrent Heterozygous LMNA p.T10I Mutation. J Clin Endocrinol Metab 103:1005-1014
Choksi, Palak; Rothberg, Amy; Kraftson, Andrew et al. (2018) Weight loss and bone mineral density in obese adults: a longitudinal analysis of the influence of very low energy diets. Clin Diabetes Endocrinol 4:14
Djuric, Zora; Bassis, Christine M; Plegue, Melissa A et al. (2018) Colonic Mucosal Bacteria Are Associated with Inter-Individual Variability in Serum Carotenoid Concentrations. J Acad Nutr Diet 118:606-616.e3
Meral, Rasimcan; Ryan, Benjamin J; Malandrino, Noemi et al. (2018) ""Fat Shadows"" From DXA for the Qualitative Assessment of Lipodystrophy: When a Picture Is Worth a Thousand Numbers. Diabetes Care 41:2255-2258
Namkoong, Sim; Ho, Allison; Woo, Yu Mi et al. (2018) Systematic Characterization of Stress-Induced RNA Granulation. Mol Cell 70:175-187.e8
Marino, Simeone; Xu, Jiachen; Zhao, Yi et al. (2018) Controlled feature selection and compressive big data analytics: Applications to biomedical and health studies. PLoS One 13:e0202674
Liu, Dongmei; Morales, Flor Elisa; IglayReger, Heidi B et al. (2018) Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. Appl Physiol Nutr Metab 43:187-193

Showing the most recent 10 out of 342 publications