The University of Iowa proposes to: 1) develop an interdisciplinary Environmental Health Sciences Research Center (EHSRC) with a focus on agricultural and rural environmental exposures and health effects; 2) promote greater research interaction between 10 existing University environmental health research units, enhance on-going environmental health research, and facilitate initiation of new collaborative and interdisciplinary environmental health research; and 3) serve as a technical resource to the State of Iowa, the region, the nation, and to international agencies in the area of agricultural and rural environmental health. The Center will involve faculty from eight departments in the Colleges of Medicine and Engineering. Its structure will include an Administrative Core; four research cores, including an Epidemiology and Biometry Core, and Environmental Assessment and Control Core, an Occupational Health Core, and a Pulmonary biology Core; and five research facilities, including a Health Registry Facility, an Environmental Measurement Facility, an Human Biomarkers Facility, a Tissue Culture Facility, and a Human Immunology Facility. Research will be promoted through use of dedicated research facilities and equipment, a formal peer review process, research coordiantion and planning, national and international scientific exchange, information transfer and communicatio, a seminar series and topical conference, a pilot project grant program, and through recruitment and stabilization of Center faculty. Five research goals for the Center include expansion of environmental cancer research with a focus on epidemiolgy, expansion of environmental birth defect and human development research with a focus on epidemiology, strengthening and extending occupational and environmental lung disease research, extension of occupational and environmental disease surveillance research, and development of a research program in the ara of international rural and environmental health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES005605-05
Application #
2154289
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1990-09-29
Project End
1996-03-31
Budget Start
1994-04-01
Budget End
1996-03-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Iowa
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Gilbert, Paul A; Laroche, Helena H; Wallace, Robert B et al. (2018) Extending Work on Rural Health Disparities: A Commentary on Matthews and Colleagues' Report. J Rural Health 34:119-121
Stapleton, Emma M; O'Shaughnessy, Patrick T; Locke, Sarah J et al. (2018) A task-based analysis of black carbon exposure in Iowa farmers during harvest. J Occup Environ Hyg 15:293-304
Li, Xueshu; Holland, Erika B; Feng, Wei et al. (2018) Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int 25:16508-16521
P?n?íková, Kate?ina; Svržková, Lucie; Strapá?ová, Simona et al. (2018) In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion. Environ Pollut 237:473-486
Andreotti, Gabriella; Koutros, Stella; Hofmann, Jonathan N et al. (2018) Glyphosate Use and Cancer Incidence in the Agricultural Health Study. J Natl Cancer Inst 110:509-516
Martinez, Carlos H; Li, Sara X; Hirzel, Andrew J et al. (2018) Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. J Allergy Clin Immunol 141:429-432
Schoenfeld, Joshua D; Sibenaller, Zita A; Mapuskar, Kranti A et al. (2018) Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models. Redox Biol 14:417-422
Brandt, Kristin E; Falls, Kelly C; Schoenfeld, Joshua D et al. (2018) Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biol 14:82-87
P?n?íková, Kate?ina; Brenerová, Petra; Svržková, Lucie et al. (2018) Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro. Environ Sci Pollut Res Int 25:16411-16419
Bao, Wei; Dar, Sharon; Zhu, Yeyi et al. (2018) Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study. J Diabetes 10:487-495

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