Since its inception in 1990, the Environmental Health Sciences Research Center (EHSRC) has advanced and translated research that addresses environmental health problems across the urban-rural continuum. The Center vision is to be the primary resource for improving the health of rural residents by stimulating and translating innovative environmental health sciences research. This is accomplished by gaining new insights into rural exposures; pathways of host defense, lung injury and repair; population health; and the toxicity of nanoscale materials; and, then translating these insights to clinical medicine, public health practice and regulatory policy. The Center goals are to: 1) Develop and expand innovative interdisciplinary environmental health sciences research in their core areas; 2) Recruit, mentor and nurture talented new investigators in environmental health sciences; and 3) Provide outreach and engagement in an effort to translate research findings toward improving the health and environment of rural dwellers. The investigators interdisciplinary research is organized around four Research Cores: Inflammation & Innate Immunity, Oxidative Stress & Metabolism, Environmental Lung Disease and Nanotoxicology. Three Facility Cores provide cutting edge services and equipment: Integrative Health Sciences Facility, Pulmonary Toxicology Facility, and Environmental Modeling & Exposure Assessment Facility. The EHSRC is at the forefront of research on environmental health problems such as environmental lung diseases, bioaerosol-induced inflammation, mechanisms of oxidative stress, innate immune responses to inhaled microbial agents, and metabolism of pesticides and other chemical agents. An Administrative Core leverages institutional support and manages the state-of-the-art Facility Cores and highly effective Pilot Grant and Career Development Programs that provide resources and mentoring to advance the careers of promising young investigators. The Community Outreach and Engagement Core engages stakeholders in bi-directional communications to ensure relevance of EHSRC research and to translate research findings to environmental public health.

Public Health Relevance

The Environmental Health Sciences Research Center (EHSRC) serves to develop careers of environmental health scientists, advance environmental health research, and translate this research to stakeholders. EHSRC investigators are devoted to advancing current knowledge of rural environmental exposures and their health effects and to translating these findings in meaningful ways for the benefit of public health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES005605-25
Application #
8832725
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Thompson, Claudia L
Project Start
1997-04-01
Project End
2017-03-31
Budget Start
2015-04-01
Budget End
2016-03-31
Support Year
25
Fiscal Year
2015
Total Cost
$1,579,155
Indirect Cost
$529,155
Name
University of Iowa
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52246
Lee, Mi Kyeong; Carnes, Megan U; Butz, Natasha et al. (2018) Exposures Related to House Dust Microbiota in a U.S. Farming Population. Environ Health Perspect 126:067001
Rosen, Bradley H; Chanson, Marc; Gawenis, Lara R et al. (2018) Animal and model systems for studying cystic fibrosis. J Cyst Fibros 17:S28-S34
Vargas Buonfiglio, Luis G; Borcherding, Jennifer A; Frommelt, Mark et al. (2018) Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance. Respir Res 19:42
Ulrich, Ethan J; Sunderland, John J; Smith, Brian J et al. (2018) Automated model-based quantitative analysis of phantoms with spherical inserts in FDG PET scans. Med Phys 45:258-276
Bao, Wei; Song, Yiqing; Bertrand, Kimberly A et al. (2018) Prepregnancy habitual intake of vitamin D from diet and supplements in relation to risk of gestational diabetes mellitus: A prospective cohort study. J Diabetes 10:373-379
Uwimana, Eric; Ruiz, Patricia; Li, Xueshu et al. (2018) HUMAN CYP2A6, CYP2B6 AND CYP2E1 ATROPSELECTIVELY METABOLIZE POLYCHLORINATED BIPHENYLS TO HYDROXYLATED METABOLITES. Environ Sci Technol :
Hofmann, Jonathan N; Shiels, Meredith S; Friesen, Melissa C et al. (2018) Industrial hog farming is associated with altered circulating immunological markers. Occup Environ Med 75:212-217
Rodriguez, Eric A; Vanle, Brigitte C; Doorn, Jonathan A et al. (2018) Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environ Toxicol Pharmacol 62:69-78
Klaren, William D; Vine, David; Vogt, Stefan et al. (2018) Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25:16427-16433
Das, Saikat; Oldham, Edward Davis; Lehmler, Hans-Joachim et al. (2018) Tuning the position of head groups by surfactant design in mixed micelles of cationic and carbohydrate surfactants. J Colloid Interface Sci 512:428-438

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