Abstract

The UNC High Throughput Genotyping Core Facility was established in 1998 as a joint collaboration of the UNC Lineberger Comprehensive Cancer Center and the School of Public Health. The original goal of the Core Facility was to conduct high-speed genotyping assays in support of epidemiologic and clinical studies of cancer. In this case, the investigators propose to increase the capacity of the facility by increasing the number of genotyping assays performed, and to expand the focus of the facility to include non-cancer outcomes.
The aims of the Core are to: 1) to make available to NIEHS Center members the services provided by the UNC High Throughput Genotyping Core Facility; 2) to increase the capacity of the High Throughput Genotyping Core Facility in order to meet the needs of NIEHS Center investigators; and, 3) to enlarge the scope of genotyping assays conducted by the Core to include markers of susceptibility to non-cancer outcomes, including reproductive health, cardiovascular disease and neurologic disease and development.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
1P30ES010126-01A1
Application #
6458276
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2001-04-01
Project End
2005-03-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Oliver-Williams, Clare; Howard, Annie Green; Navas-Acien, Ana et al. (2018) Cadmium body burden, hypertension, and changes in blood pressure over time: results from a prospective cohort study in American Indians. J Am Soc Hypertens 12:426-437.e9
Mayne, Stephanie L; Auchincloss, Amy H; Tabb, Loni Philip et al. (2018) Associations of Bar and Restaurant Smoking Bans With Smoking Behavior in the CARDIA Study: A 25-Year Study. Am J Epidemiol 187:1250-1258
Gray, Kathleen M (2018) From Content Knowledge to Community Change: A Review of Representations of Environmental Health Literacy. Int J Environ Res Public Health 15:
Pace, Nelson D; Desrosiers, Tania A; Carmichael, Suzan L et al. (2018) Antioxidant Consumption is Associated with Decreased Odds of Congenital Limb Deficiencies. Paediatr Perinat Epidemiol 32:90-99
Zheng, Xiaojing; O'Connell, Catherine M; Zhong, Wujuan et al. (2018) Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. J Immunol 200:2941-2956
Orlow, Irene; Shi, Yang; Kanetsky, Peter A et al. (2018) The interaction between vitamin D receptor polymorphisms and sun exposure around time of diagnosis influences melanoma survival. Pigment Cell Melanoma Res 31:287-296
Herceg, Zdenko; Ghantous, Akram; Wild, Christopher P et al. (2018) Roadmap for investigating epigenome deregulation and environmental origins of cancer. Int J Cancer 142:874-882
Tappata, Manaswita; Eluri, Swathi; Perjar, Irina et al. (2018) Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy 73:2088-2092
Little, Michael S; Pellock, Samuel J; Walton, William G et al. (2018) Structural basis for the regulation of ?-glucuronidase expression by human gut Enterobacteriaceae. Proc Natl Acad Sci U S A 115:E152-E161
Hoffman, Kate; Stapleton, Heather M; Lorenzo, Amelia et al. (2018) Prenatal exposure to organophosphates and associations with birthweight and gestational length. Environ Int 116:248-254

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