Abstract

The goal of the Biomarker Facility Core is to provide access to state of the art facilities for mass spectrometry, microarray, proteomics, metabolomics, mouse genotyping, DNA damage and immunohistochemistry for members of the CEHS to facilitate and enhance research on environmentally related disease. This will be accomplished by the following objectives: 1) to make available to Center members well equipped laboratories for analytical, molecular, genomic and histochemical biomarkers; 2) to assist Center members with experimental design, tissue collection and assays of various biomarkers; 3) to foster the application of biomarkers in pilot projects and new collaborative research projects; 4) to provide education and training in methods related to biomarkers.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES010126-06
Application #
7311975
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
6
Fiscal Year
2006
Total Cost
$303,122
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Tennyson, Robert L; Gettler, Lee T; Kuzawa, Christopher W et al. (2018) Lifetime socioeconomic status and early life microbial environments predict adult blood telomere length in the Philippines. Am J Hum Biol 30:e23145
Thomas, Nancy E; Edmiston, Sharon N; Orlow, Irene et al. (2018) Inherited Genetic Variants Associated with Melanoma BRAF/NRAS Subtypes. J Invest Dermatol 138:2398-2404
Porrello, Alessandro; Leslie, Patrick L; Harrison, Emily B et al. (2018) Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Nat Commun 9:1988
Manuck, Tracy A; Smeester, Lisa; Martin, Elizabeth M et al. (2018) Epigenetic Regulation of the Nitric Oxide Pathway, 17-? Hydroxyprogesterone Caproate, and Recurrent Preterm Birth. Am J Perinatol 35:721-728
Barrington, William T; Wulfridge, Phillip; Wells, Ann E et al. (2018) Improving Metabolic Health Through Precision Dietetics in Mice. Genetics 208:399-417
Cui, Tianqu; Zeng, Zhexi; Dos Santos, Erickson O et al. (2018) Development of a hydrophilic interaction liquid chromatography (HILIC) method for the chemical characterization of water-soluble isoprene epoxydiol (IEPOX)-derived secondary organic aerosol. Environ Sci Process Impacts 20:1524-1536
Robbins, Zachary; Bodnar, Wanda; Zhang, Zhenfa et al. (2018) Trisaminohexyl isocyanurate, a urinary biomarker of HDI isocyanurate exposure. J Chromatogr B Analyt Technol Biomed Life Sci 1076:117-129
Pietryk, Edward W; Clement, Kiristin; Elnagheeb, Marwa et al. (2018) Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme. Reprod Toxicol 78:9-19
Marks, Daniel L; Blackmon, Richard L; Oldenburg, Amy L (2018) Diffusion tensor optical coherence tomography. Phys Med Biol 63:025007
Sarnowski, Chloé; Kavousi, Maryam; Isaacs, Steve et al. (2018) Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women. Menopause 25:451-457

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