Abstract

The Imaging Core provides CVS faculty with access to equipment and highly trained staff that support histology, human and animal imaging, and adaptive optics for psychophysics and retinal imaging. The Imaging Core is sub-divided into three facilities. The Histology/Microscopy Facility supports brain and ocular tissue harvesting, processing, staining and microscopic examination (qualitative and quantitative). It is staffed by Tracy Bubel with over 24 years of experience in this area. The In Vivo Imaging Facility provides access to instruments for anterior segment, retinal, and brain imaging in addition to functional assessments of vision. The Adaptive Optics (AO) Facility consists of cutting-edge instrumentation utilising adaptive optics for visual psychophysics and cellular-scale retinal imaging. The AO Facility is staffed by two highly qualified engineers, Jie Zhang, Ph.D., and Qiang Yang, Ph.D. Through these three Facilities, the Imaging Core meets the expanding imaging requirements for advanced vision research and clinical research applications by CVS Core users.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001319-46
Application #
10016320
Study Section
Special Emphasis Panel (ZEY1)
Project Start
1997-03-01
Project End
2023-08-31
Budget Start
2020-09-01
Budget End
2021-08-31
Support Year
46
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Song, Hongxin; Rossi, Ethan A; Stone, Edwin et al. (2018) Phenotypic diversity in autosomal-dominant cone-rod dystrophy elucidated by adaptive optics retinal imaging. Br J Ophthalmol 102:136-141
Schwarz, Christina; Sharma, Robin; Cheong, Soon Keen et al. (2018) Selective S Cone Damage and Retinal Remodeling Following Intense Ultrashort Pulse Laser Exposures in the Near-Infrared. Invest Ophthalmol Vis Sci 59:5973-5984
Cheong, Soon Keen; Strazzeri, Jennifer M; Williams, David R et al. (2018) All-optical recording and stimulation of retinal neurons in vivo in retinal degeneration mice. PLoS One 13:e0194947
Granger, Charles E; Yang, Qiang; Song, Hongxin et al. (2018) Human Retinal Pigment Epithelium: In Vivo Cell Morphometry, Multispectral Autofluorescence, and Relationship to Cone Mosaic. Invest Ophthalmol Vis Sci 59:5705-5716
Cheong, Soon K; Xiong, Wenjun; Strazzeri, Jennifer M et al. (2018) In Vivo Functional Imaging of Retinal Neurons Using Red and Green Fluorescent Calcium Indicators. Adv Exp Med Biol 1074:135-144
Zinszer, Benjamin D; Bayet, Laurie; Emberson, Lauren L et al. (2018) Decoding semantic representations from functional near-infrared spectroscopy signals. Neurophotonics 5:011003
McGregor, Juliette E; Yin, Lu; Yang, Qiang et al. (2018) Functional architecture of the foveola revealed in the living primate. PLoS One 13:e0207102
Lockwood, Colin T; Vaughn, William; Duffy, Charles J (2018) Attentional ERPs distinguish aging and early Alzheimer's dementia. Neurobiol Aging 70:51-58
Chernoff, Benjamin L; Teghipco, Alex; Garcea, Frank E et al. (2018) A Role for the Frontal Aslant Tract in Speech Planning: A Neurosurgical Case Study. J Cogn Neurosci 30:752-769
Alarcon-Martinez, Luis; Yilmaz-Ozcan, Sinem; Yemisci, Muge et al. (2018) Capillary pericytes express ?-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection. Elife 7:

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