Abstract

CELLULAR AND MOLECULAR BIOLOGY CORE The Cellular and Molecular Biology Core provides essential equipment and support for molecular biology, cell culture, histology, and virology. Importantly, the Core contains a number of specialized instruments that are either too costly for individual investigators, necessary but infrequently used, or require skilled assistance to use. The goals are to provide facilities, expertise, and services for: 1) establishing, expanding, and maintaining primary cells, stem cells, and transformed, transfected, and inducible cell lines as well as organ cultures for use in vision research, 2) performing cellular and molecular biology experiments for ophthalmic research that require use of specialized instrumentation, 3) assisting and coordinating experiments that involve cell culturing, transfection, viral packaging, primer design, cloning, construction of mammalian and viral vectors, flow cytometry, laser capture microdissection, DNA sequencing, real time PCR, DNA/microRNA microarray, Luminex, proteomics, and protein analyses, and 4) assisting in histologic and morphological studies of tissue specimens and cultured cells.

Public Health Relevance

CELLULAR AND MOLECULAR BIOLOGY CORE The Cellular and Molecular Biology Core provides facilities, equipment, and support for cellular and molecular biology to augment research capacity and increase productivity of investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001792-40
Application #
9772470
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2019-09-30
Budget End
2020-09-29
Support Year
40
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
University of Illinois at Chicago
Department
Type
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

McAnany, J Jason; Park, Jason C (2018) Reduced Contrast Sensitivity is Associated With Elevated Equivalent Intrinsic Noise in Type 2 Diabetics Who Have Mild or No Retinopathy. Invest Ophthalmol Vis Sci 59:2652-2658
Zhang, Min; Zhou, Qiang; Luo, Yuncin et al. (2018) Semaphorin3A induces nerve regeneration in the adult cornea-a switch from its repulsive role in development. PLoS One 13:e0191962
McAnany, J Jason; Park, Jason C (2018) Temporal Frequency Abnormalities in Early-Stage Diabetic Retinopathy Assessed by Electroretinography. Invest Ophthalmol Vis Sci 59:4871-4879
Patangay, Shresta; Derafshi, Zahra; Vajaranant, Thasarat S et al. (2018) Three Dimensional Stimulus Source for Pattern Electroretinography in Mid- and Far-peripheral Retina. Transl Vis Sci Technol 7:8
Ali, Mohsin H; Azar, Nathalie F; Aakalu, Vinay et al. (2018) Congenital cavitary optic disc anomaly and Axenfeld's anomaly in Wolf-Hirschhorn syndrome: A case report and review of the literature. Ophthalmic Genet 39:271-274
Nannini, Drew R; Kim, Heejin; Fan, Fangda et al. (2018) Genetic Risk Score Is Associated with Vertical Cup-to-Disc Ratio and Improves Prediction of Primary Open-Angle Glaucoma in Latinos. Ophthalmology 125:815-821
Calway, Tyler; Rubin, Daniel S; Moss, Heather E et al. (2018) Perioperative Retinal Artery Occlusion: Incidence and Risk Factors in Spinal Fusion Surgery From the US National Inpatient Sample 1998-2013. J Neuroophthalmol 38:36-41
Park, Jason C; Moss, Heather E; McAnany, J Jason (2018) Electroretinography in idiopathic intracranial hypertension: comparison of the pattern ERG and the photopic negative response. Doc Ophthalmol 136:45-55
Rouhbakhshzaeri, Majid; Rabiee, Behnam; Azar, Nathalie et al. (2018) New ex vivo model of corneal endothelial phacoemulsification injury and rescue therapy with mesenchymal stromal cell secretome. J Cataract Refract Surg :
Samaeekia, Ravand; Rabiee, Behnam; Putra, Ilham et al. (2018) Effect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing. Invest Ophthalmol Vis Sci 59:5194-5200

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