The Administrative Core supports the overall management of the P30 Center Core Grant. The Core is directed by the P30 Grant PI and includes the Executive Committee (comprised of the PI and Module Directors), the Module Managers, the Advisory Committee, and administrative staff. The Executive Committee oversees the day-to-day operations of the four grant Modules, which are run by highly experienced Module Managers. Each of the Module Directors meets with the Module Manager(s) under his/her supervision at least once a week or on as needed basis, if any issues arise to quickly resolve these issues. In addition, Module Managers meet bi- monthly with the P30 PI and administrative staff to discus module usage and budget, equipment maintenance, repair and service contracts as well as any other activities related to the operations of the Modules. Also, there is once a year a meeting of the P30 PI, Executive Committee and Advisory Committee to evaluate the P30 grant services in terms of their effectiveness and fair use of the P30 resources as well as to make strategic decisions pertaining to the P30 grant operations such as introduction of a new module or module services, discontinuation of an existing module because of under utilization, major equipment purchase, and investment in new technologies. Finally, the Executive Committee receives a direct feedback from the Module users during the monthly meetings of the Visual Sciences Research Center PIs.

National Institute of Health (NIH)
National Eye Institute (NEI)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Case Western Reserve University
United States
Zip Code
Mallory, D Paul; Gutierrez, Elizabeth; Pinkevitch, Margaret et al. (2018) The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State. Biochemistry 57:5188-5201
Linetsky, Mikhail; Bondelid, Karina S; Losovskiy, Sofiya et al. (2018) 4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells. Chem Res Toxicol 31:666-679
Choi, Elliot H; Suh, Susie; Sander, Christopher L et al. (2018) Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Hum Mol Genet 27:2225-2243
Zhang, Lingjun; Li, Yan; Qiu, Wen et al. (2018) Targeting CD6 for the treatment of experimental autoimmune uveitis. J Autoimmun 90:84-93
Orban, Tivadar; Leinonen, Henri; Getter, Tamar et al. (2018) A Combination of G Protein-Coupled Receptor Modulators Protects Photoreceptors from Degeneration. J Pharmacol Exp Ther 364:207-220
Samanta, Amrita; Kiselar, Janna; Pumroy, Ruth A et al. (2018) Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition. J Gen Physiol 150:751-762
Saadane, Aicha; Petrov, Alexey; Mast, Natalia et al. (2018) Mechanisms that minimize retinal impact of apolipoprotein E absence. J Lipid Res 59:2368-2382
Sun, Yan; Abbondante, Serena; Karmakar, Mausita et al. (2018) Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1? in Aspergillus fumigatus Infection. J Immunol 201:2767-2775
Nahomi, Rooban B; Sampathkumar, Sruthi; Myers, Angela M et al. (2018) The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice. Invest Ophthalmol Vis Sci 59:2042-2053
Kiser, Philip D; Zhang, Jianye; Sharma, Aditya et al. (2018) Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function. J Gen Physiol 150:571-590

Showing the most recent 10 out of 510 publications