- Overall Core Brookhaven National Laboratory has developed a world-leading suite of experimental facilities for the life- science research community. Much of it is organized in the Center for Biomolecular Structure (CBMS), which has a focus on macromolecular crystallography (MX) and x-ray scattering, with a user program of imaging in biological materials: fluorescence imaging of metals, and full-field absorption and phase-contrast imaging on all materials. We exploit the unprecedentedly small, bright, and well-collimated x-ray beams of National Synchrotron Light Source II (NSLS-II) with experimental stations that provide the best possible crystal- diffraction and x-ray scattering data with high levels of automation. Our responsibility to the users is to enable hypothesis-driven research by having sufficient throughput to support high-volume systematic studies, and with the capability, through our assembly of diverse beamlines, to support multi-disciplinary work for complex investigations.

Public Health Relevance

- Overall Core The Center for Biomolecular Structure (CBMS) presents state-of-the-art structural biology facilities at the National Synchrotron Light Source II (NSLS-II) to the world-wide community of researchers interested in the study of biological structure. These facilities include 1. micro-beam and highly automated macromolecular crystallography, 2. several modes of x-ray scattering from non-crystalline material, including from solutions, scattering images from tissues, and others, and 3. imaging by x-ray fluorescence at a range of energies and resolution scales, and full-field imaging.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
5P30GM133893-02
Application #
10002280
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Smith, Ward
Project Start
2019-09-01
Project End
2024-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
2
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Brookhaven National Laboratory
Department
Type
DUNS #
027579460
City
Upton
State
NY
Country
United States
Zip Code
11973