Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
High Priority, Short Term Project Award (R56)
Project #
1R56DK071711-01
Application #
7093433
Study Section
Cellular Aspects of Diabetes and Obesity Study Section (CADO)
Program Officer
Haft, Carol R
Project Start
2005-08-15
Project End
2006-07-31
Budget Start
2005-08-15
Budget End
2006-07-31
Support Year
1
Fiscal Year
2005
Total Cost
$116,250
Indirect Cost
Name
University of Illinois at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
Huang, Zhi H; Reardon, Catherine A; Subbaiah, Papasani V et al. (2013) ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice. J Lipid Res 54:202-13
Yue, Lili; Bian, Jing-Tan; Grizelj, Ivana et al. (2012) Apolipoprotein E enhances endothelial-NO production by modulating caveolin 1 interaction with endothelial NO synthase. Hypertension 60:1040-6
Huang, Zhi H; Maeda, Nobuyo; Mazzone, Theodore (2011) Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipogenesis. J Lipid Res 52:1733-41
Yue, Lili; Mazzone, Theodore (2011) Endogenous adipocyte apolipoprotein E is colocalized with caveolin at the adipocyte plasma membrane. J Lipid Res 52:489-98
Huang, Zhi H; Espiritu, Doris J; Uy, Arlene et al. (2011) Adipose tissue depot-specific differences in adipocyte apolipoprotein E expression. Metabolism 60:1692-701
Mazzone, Theodore (2010) Intensive glucose lowering and cardiovascular disease prevention in diabetes: reconciling the recent clinical trial data. Circulation 122:2201-11
Espiritu, Doris Joy; Huang, Zhi Hua; Zhao, Yong et al. (2010) Hyperglycemia and advanced glycosylation end products suppress adipocyte apoE expression: implications for adipocyte triglyceride metabolism. Am J Physiol Endocrinol Metab 299:E615-23
Yue, Lili; Mazzone, Theodore (2009) Peroxisome proliferator-activated receptor {gamma} stimulation of adipocyte ApoE gene transcription mediated by the liver receptor X pathway. J Biol Chem 284:10453-61
Sam, Susan; Haffner, Steven; Davidson, Michael H et al. (2009) Hypertriglyceridemic waist phenotype predicts increased visceral fat in subjects with type 2 diabetes. Diabetes Care 32:1916-20
Huang, Zhi Hua; Minshall, Richard D; Mazzone, Theodore (2009) Mechanism for endogenously expressed ApoE modulation of adipocyte very low density lipoprotein metabolism: role in endocytic and lipase-mediated metabolic pathways. J Biol Chem 284:31512-22

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