Abstract

The Behavioral Science Core has two objectives: to enhance the integrity of the independent variables of research involving human subjects (especially children and youth) where cooperation (compliance, adherence) represents a serious confound or barrier; and to expand the range and type of dependent variables by making available state-of-the- science methods so that investigators can objectively quantify behavioral phenomena specific to mental retardation and related disorders and identify, track and compare cognitive, behavioral, and developmental characteristics of genetic phenotypes, syndromes, diagnoses, intervention approaches, and animal models. The first objective is achieved by antecedent stimulus control procedures and contingency shaping procedures; the second by selection and use of standardized assessment procedures, direct observation techniques, and computer performance tasks designed to assess psychological variables.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD024061-15
Application #
6654159
Study Section
Project Start
2002-08-01
Project End
2003-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
15
Fiscal Year
2002
Total Cost
$131,864
Indirect Cost

  Institution

Name
Hugo W. Moser Research Institute Kennedy Krieger
Department
Type
DUNS #
167202410
City
Baltimore
State
MD
Country
United States
Zip Code
21205

  Publications

Jenkins, Edmund C; Ye, Lingling; Krinsky-McHale, Sharon J et al. (2016) Telomere longitudinal shortening as a biomarker for dementia status of adults with Down syndrome. Am J Med Genet B Neuropsychiatr Genet 171B:169-74
Schneider, Heather E; Lam, Janet C; Mahone, E Mark (2016) Sleep disturbance and neuropsychological function in young children with ADHD. Child Neuropsychol 22:493-506
Sweda, Romy; Phillips, Andre W; Marx, Joel et al. (2016) Glial-Restricted Precursors Protect Neonatal Brain Slices from Hypoxic-Ischemic Cell Death Without Direct Tissue Contact. Stem Cells Dev 25:975-85
Gaddis, Andrew; Rosch, Keri S; Dirlikov, Benjamin et al. (2015) Motor overflow in children with attention-deficit/hyperactivity disorder is associated with decreased extent of neural activation in the motor cortex. Psychiatry Res 233:488-95
Porambo, Michael; Phillips, Andre W; Marx, Joel et al. (2015) Transplanted glial restricted precursor cells improve neurobehavioral and neuropathological outcomes in a mouse model of neonatal white matter injury despite limited cell survival. Glia 63:452-65
Diehl, Adam; Mu, Weiyi; Batista, Denise et al. (2015) An atypical 0.73 MB microduplication of 22q11.21 and a novel SALL4 missense mutation associated with thumb agenesis and radioulnar synostosis. Am J Med Genet A 167:1644-9
Koriakin, Taylor A; Mahone, E Mark; Jacobson, Lisa A (2015) Sleep Difficulties are Associated with Parent Report of Sluggish Cognitive Tempo. J Dev Behav Pediatr 36:717-23
Reinblatt, Shauna P; Mahone, E Mark; Tanofsky-Kraff, Marian et al. (2015) Pediatric loss of control eating syndrome: Association with attention-deficit/hyperactivity disorder and impulsivity. Int J Eat Disord 48:580-8
Walsh, D M; Doran, E; Silverman, W et al. (2015) Rapid assessment of cognitive function in down syndrome across intellectual level and dementia status. J Intellect Disabil Res 59:1071-9
Benbadis, Selim R; Ewen, Joshua B; Schreiber, John M et al. (2015) Variations in EEG discharges predict ADHD severity within individual Smith-Lemli-Opitz patients. Neurology 84:436

Showing the most recent 10 out of 376 publications