The Developmental Psychobiology Core will integrate biological measures of developmental status, reactivity, and endocrine regulation, with the assessments of psychiatric status and environment available from the other Cores and existing shared samples and datasets, to build and test models concerning the developmental epidemiology of psychiatric risk. The combined investigative resources of the Center provide an unparalleled opportunity to effect a genuine synthesis of biological with contextual measures, and to probe their relationships in the development of behavior and its disorders. Further, techniques and data sets for quantitative behavioral genetics with biological measures of developmental status, reactivity, and hormone bio-availability will allow estimation of their genetic and environmental components, and an opportunity to parse contributions of shared and non-shared environment.
Eaves, Lindon; Verhulst, Brad (2014) Problems and pit-falls in testing for G × E and epistasis in candidate gene studies of human behavior. Behav Genet 44:578-90 |
Eaves, Lindon J; Pourcain, Beate St; Smith, George Davey et al. (2014) Resolving the effects of maternal and offspring genotype on dyadic outcomes in genome wide complex trait analysis (""M-GCTA""). Behav Genet 44:445-55 |
Worthman, Carol M (2009) Habits of the heart: life history and the developmental neuroendocrinology of emotion. Am J Hum Biol 21:772-81 |
Worthman, Carol M; Costello, E Jane (2009) Tracking biocultural pathways in population health: the value of biomarkers. Ann Hum Biol 36:281-97 |
Costello, E J; Keeler, G P; Angold, A (2001) Poverty, race/ethnicity, and psychiatric disorder: a study of rural children. Am J Public Health 91:1494-8 |
Costello, E J; Angold, A (2000) Developmental psychopathology and public health: past, present, and future. Dev Psychopathol 12:599-618 |