A. Introduction. The Operations Core (OC) is designed to integrate the scientific and research capacity aims of the ACISR and meet NIH's program announcement requirements. This core includes administrative functions, data management and statistical analysis, and dissemination activities. We describe community liaisons, clinical trials operations, mentorship and training and two specialized components. Our OC is designed to foster an environment of research excellence, support methodological innovation, facilitate multidisciplinary collaborations, coordinate efforts, and monitor progress according to a focused research agenda. The administrative structure supports work which will be largely conducted in the Research Methods Core (RMC) and Principal Research Core (PRC). The Core builds on our successful administrative structures in the Bipolar DCISR and SPARC.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Center Core Grants (P30)
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Special Emphasis Panel (ZMH1)
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University of Texas Health Science Center
San Antonio
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Fries, Gabriel R; Colpo, Gabriela D; Monroy-Jaramillo, Nancy et al. (2017) Distinct lithium-induced gene expression effects in lymphoblastoid cell lines from patients with bipolar disorder. Eur Neuropsychopharmacol 27:1110-1119
Fang, Fang; Wang, Zuowei; Wu, Renrong et al. (2017) Is there a 'weight neutral' second-generation antipsychotic for bipolar disorder? Expert Rev Neurother 17:407-418
Tohen, Mauricio; Mintz, Jim; Bowden, Charles L (2016) Analysis of bipolar maintenance treatment with lithium versus olanzapine utilizing Multi-state Outcome Analysis of Treatments (MOAT). Bipolar Disord 18:282-7
Arnold, Jodi Gonzalez; Martinez, Cervando; Zavala, Juan et al. (2016) Investigating symptom domains of bipolar disorder for Spanish-speakers using the Bipolar Inventory of Symptoms Scale. J Affect Disord 205:239-244
Perlick, Deborah A; Berk, Lesley; Kaczynski, Richard et al. (2016) Caregiver burden as a predictor of depression among family and friends who provide care for persons with bipolar disorder. Bipolar Disord 18:183-91
Bowden, C L; Mintz, J; Tohen, M (2016) Multi-state outcome analysis of treatments (MOAT): application of a new approach to evaluate outcomes in longitudinal studies of bipolar disorder. Mol Psychiatry 21:237-42
Bowden, Charles L; Singh, Vivek (2016) The use of antidepressants in bipolar disorder patients with depression. Expert Opin Pharmacother 17:17-25
Gonzalez Arnold, Jodi; Salcedo, Stephanie; Ketter, Terrence A et al. (2015) An exploratory study of responses to low-dose lithium in African Americans and Hispanics. J Affect Disord 178:224-8
Bowden, Charles L (2015) Providing assessable information on effectiveness of maintenance treatments for bipolar disorder to psychiatrists and patients. Evid Based Ment Health 18:58
Singh, V; Bowden, C L; Gonzalez, J M et al. (2013) Discriminating primary clinical states in bipolar disorder with a comprehensive symptom scale. Acta Psychiatr Scand 127:145-52

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