Abstract

The Electron Microscopy Core enables neuroscientists to visualize neural circuit structure with nanometer resolution using traditional transmission electron microscopy and the high-throughput electron microscopy developed at Harvard for Connectomics. Like the Light Microscopy Core, the Electron Microscopy Core enables valuable neuroscience research and promotes a new model for interdisciplinary neuroscience, ultimately to address fundamental issues of human health.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS062685-09
Application #
9269260
Study Section
Special Emphasis Panel (ZNS1)
Project Start
2008-09-15
Project End
2018-12-31
Budget Start
2017-01-01
Budget End
2017-12-31
Support Year
9
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
Harvard University
Department
Type
DUNS #
082359691
City
Cambridge
State
MA
Country
United States
Zip Code
02138

  Publications

Sarin, Sumeet; Zuniga-Sanchez, Elizabeth; Kurmangaliyev, Yerbol Z et al. (2018) Role for Wnt Signaling in Retinal Neuropil Development: Analysis via RNA-Seq and In Vivo Somatic CRISPR Mutagenesis. Neuron 98:109-126.e8
Hildebrand, David Grant Colburn; Cicconet, Marcelo; Torres, Russel Miguel et al. (2017) Whole-brain serial-section electron microscopy in larval zebrafish. Nature 545:345-349
Duan, Xin; Qiao, Mu; Bei, Fengfeng et al. (2015) Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling. Neuron 85:1244-56
Roberts, Mike; Jeong, Won-Ki; Vazquez-Reina, Amelio et al. (2011) Neural process reconstruction from sparse user scribbles. Med Image Comput Comput Assist Interv 14:621-8
Jeong, Won-Ki; Schneider, Jens; Turney, Stephen G et al. (2010) Interactive histology of large-scale biomedical image stacks. IEEE Trans Vis Comput Graph 16:1386-95