Abstract

IMAGE AND SPECTROSCOPY ANALYSIS AND VISUALIZATION CORE PI: Christophe Lenglet, PhD;co-PI: Noam Harel, PhD This Core will provide advanced analysis tools and resources for a variety of neuroimaging modalities including structural MRI, High Angular Resolution Diffusion Imaging (HARDI), Diffusion Spectroscopic Imaging (DSI), functional MRI (fMRI), intrinsic relaxation parameter imaging, MR spectroscopy (MRS), as well as Positron Emission Tomography (PET) and Computed Tomography (CT). The unique needs of each of these modalities will be served through shared computing equipment, software and expert personnel in the Core. Additionally, the Core will provide support for multi-modality image analysis. Image reconstruction, analysis and visualization require sophisticated mathematical modeling and computational resources. The overall goal of this Core is to provide such unique resources for human and animal neuroimaging research. They will enable individuals to generate high-quality images from high (3 and 4T) and ultrahigh (7T and higher) field MR scanners and to efficiently analyze them through state-of-the-art methods.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS076408-02
Application #
8551753
Study Section
Special Emphasis Panel (ZNS1-SRB-R)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
2
Fiscal Year
2013
Total Cost
$154,856
Indirect Cost
$37,758

  Institution

Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Gulban, Omer F; De Martino, Federico; Vu, An T et al. (2018) Cortical fibers orientation mapping using in-vivo whole brain 7?T diffusion MRI. Neuroimage 178:104-118
Duchin, Yuval; Shamir, Reuben R; Patriat, Remi et al. (2018) Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI. PLoS One 13:e0201469
Coles, Lisa D; Tuite, Paul J; Öz, Gülin et al. (2018) Repeated-Dose Oral N-Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress. J Clin Pharmacol 58:158-167
Herzberg, Max P; Hodel, Amanda S; Cowell, Raquel A et al. (2018) Risk taking, decision-making, and brain volume in youth adopted internationally from institutional care. Neuropsychologia 119:262-270
Milham, Michael P; Ai, Lei; Koo, Bonhwang et al. (2018) An Open Resource for Non-human Primate Imaging. Neuron 100:61-74.e2
Patriat, Rémi; Cooper, Scott E; Duchin, Yuval et al. (2018) Individualized tractography-based parcellation of the globus pallidus pars interna using 7T MRI in movement disorder patients prior to DBS surgery. Neuroimage 178:198-209
Park, Young Woo; Deelchand, Dinesh K; Joers, James M et al. (2018) AutoVOI: real-time automatic prescription of volume-of-interest for single voxel spectroscopy. Magn Reson Med 80:1787-1798
Marja?ska, Ma?gorzata; Deelchand, Dinesh K; Hodges, James S et al. (2018) Altered macromolecular pattern and content in the aging human brain. NMR Biomed 31:
U?urbil, Kamil (2018) Imaging at ultrahigh magnetic fields: History, challenges, and solutions. Neuroimage 168:7-32
Peña, Edgar; Zhang, Simeng; Patriat, Remi et al. (2018) Multi-objective particle swarm optimization for postoperative deep brain stimulation targeting of subthalamic nucleus pathways. J Neural Eng 15:066020

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