The mission for the NIH BioMEMS Resource Center (BMRC) is to bridge between microelectromechanicai systems (MEMS) and biomedical community to provide powerful microtechnologies to biomedical and clinical investigators. At its inception, the focus of the BMRC research was on the development of microfluidic chips for cell sorting, especially for fractionation of blood into its key components as well as the creation of living single cell arrays. In 2008, BMRC was renewed to expand its research portfolio to include rare cells with tremendous clinical potential, and more complex dynamic tissue microarrays. As we lool

Public Health Relevance

MRC continues to represent a significant potential for biomedical advances through its mission to develop and disseminate innovative microtechnologies with a broad range of applications varying from diagnostics, therapeutics, biomarker discovery, drug screening to disease models.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Biotechnology Resource Grants (P41)
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Special Emphasis Panel (ZEB1)
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Hunziker, Rosemarie
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Massachusetts General Hospital
United States
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Wang, Xiao; Jodoin, Emily; Jorgensen, Julianne et al. (2018) Progressive mechanical confinement of chemotactic neutrophils induces arrest, oscillations, and retrotaxis. J Leukoc Biol 104:1253-1261
Weng, Lindong; Stott, Shannon L; Toner, Mehmet (2018) Molecular Dynamics at the Interface between Ice and Poly(vinyl alcohol) and Ice Recrystallization Inhibition. Langmuir 34:5116-5123
Jorfi, Mehdi; D'Avanzo, Carla; Tanzi, Rudolph E et al. (2018) Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease. Sci Rep 8:2450
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Kang, Young Bok Abraham; Eo, Jinsu; Mert, Safak et al. (2018) Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes. Sci Rep 8:8951
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Ellett, Felix; Jorgensen, Julianne; Marand, Anika L et al. (2018) Diagnosis of sepsis from a drop of blood by measurement of spontaneous neutrophil motility in a microfluidic assay. Nat Biomed Eng 2:207-214
Huang, Haishui; Yarmush, Martin L; Usta, O Berk (2018) Long-term deep-supercooling of large-volume water and red cell suspensions via surface sealing with immiscible liquids. Nat Commun 9:3201

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