P22 capsid bacteriophage and herpes virus capsid particules have icosahedral symmetry, of which the Baylor group has taken advantage to reveal the low-resolution structure by electron microscopy. We have conducted preliminary solution scattering studies on these virus particles, aimed at acquisition of scattering amplitude which is difficult to get at high resolution from electron microscopy because of the contribution of inelastic scattering. We intend to refine the EM low-resolution structure with the amplitude information obtained from solution scattering. An experimental proposal has been submitted to expand these studies.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR001209-17
Application #
5222864
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
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