SuccinateUbiquinone Oxidoreductase is a large membrane protein complex which introduces reducing equivalents from succinate into the mitochondrial respiratory chain. It comprises succinate dehydrogenase of the Krebs cycle (flavoprotein and ironsulfur protein subunits) as well as two hydrophobic membrane proteins, one of which carries protoheme. It is evolutionarily related to fumarate reductase present in many bacteria. We have crystallized it in an orthorhombic form diffracting to 3.5 E.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR001209-22
Application #
6437652
Study Section
Project Start
2001-03-01
Project End
2002-02-28
Budget Start
Budget End
Support Year
22
Fiscal Year
2001
Total Cost
$143,176
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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