A project has been initiated with Dr. Narayanswami at Jackson Labs which involves the development of a procedure for fluorescence in-situ hybridization (FISH) of chromosomes for flow karyotype analysis. Normal FISH procedures performed on chromosomes in suspension render the sample useless for flow karyotype analysis and chromosome sorting. By placing single chromosomes in an alginate matrix for the hybridization step it is now, for the first time, possible to apply FISH to chromosomes in suspension.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR001315-14
Application #
5223176
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
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