Core - Stable Lead Isotope and Trace Element Analysis

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Abstract

(Taken from application) This analytical core will be housed at Lamont-Doherty Earth Observatory (LDEO) and will provide sample preparation and analyses to multiple projects of this Superfund application. This core will primarily support Project 8 (Persistent organochlorines in the Hudson River Watershed) and Project 2 (Sources and pathways of heavy metal exposure in the Hudson River Watershed and New York City). In addition, exploratory Pb isotope analyses will be made on pre-ashed blood samples from Project 3 in year 3. If these exploratory analyses prove useful, then supplemental funding will be sought at that time to expand the number of Pb isotope analyses being run for Project 3. Sample preparation will include the following matrixes: soil, sediment and particulate matter filters, as well as sample preparation on a limited number of pre-ashed blood samples. Work to be performed for Projects 8 and 2 include sample preparation and radionuclide measurements via gamma spectroscopy and stable Pb isotope measurements. Additional analyses to be performed for Project 2 include Hg concentration and multi-element analyses by flame AA and ICP-MS. Work to be performed for Project 3 in Year 3 includes sample preparation and Pb isotope analysis of pre-ashed blood samples.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
• Project #: 3P42ES007384-07S1
• Application #: 6587638
• Project Start: 2002-04-15
• Project End: 2003-03-31
• Budget Start: 1998-10-01
• Budget End: 1999-09-30
• Support Year: 7
• Fiscal Year: 2002
• Total Cost: $83,712

Institution

• Name: Mount Sinai School of Medicine
• City: New York
• State: NY
• Country: United States
• Zip Code: 10029

Publications

Yan, Beizhan; Bopp, Richard F; Abrajano, Teofilo A et al. (2014) Source apportionment of polycyclic aromatic hydrocarbons (PAHs) into Central Park Lake, New York City, over a century of deposition. Environ Toxicol Chem 33:985-92

Miller, Todd R; Colquhoun, David R; Halden, Rolf U (2010) Identification of wastewater bacteria involved in the degradation of triclocarban and its non-chlorinated congener. J Hazard Mater 183:766-72

Miller, Todd R; Heidler, Jochen; Chillrud, Steven N et al. (2008) Fate of triclosan and evidence for reductive dechlorination of triclocarban in estuarine sediments. Environ Sci Technol 42:4570-6

Landrigan, Philip J; Forman, Joel; Galvez, Maida et al. (2008) Impact of September 11 World Trade Center disaster on children and pregnant women. Mt Sinai J Med 75:129-34

Louchouarn, Patrick; Chillrud, Steven N; Houel, Stephane et al. (2007) Elemental and molecular evidence of soot- and char-derived black carbon inputs to New York City's atmosphere during the 20th century. Environ Sci Technol 41:82-7

Grandjean, P; Landrigan, P J (2006) Developmental neurotoxicity of industrial chemicals. Lancet 368:2167-78

Wallenstein, Sylvan; Chen, Jia; Wetmur, James G (2006) Comparison of statistical models for analyzing genotype, inferred haplotype, and molecular haplotype data. Mol Genet Metab 89:270-3

Trasande, Leonardo; Schechter, Clyde; Haynes, Karla A et al. (2006) Applying cost analyses to drive policy that protects children: mercury as a case study. Ann N Y Acad Sci 1076:911-23

Ma, Risheng; Sassoon, David A (2006) PCBs exert an estrogenic effect through repression of the Wnt7a signaling pathway in the female reproductive tract. Environ Health Perspect 114:898-904

Gobeille, Alayne K; Morland, Kimberly B; Bopp, Richard F et al. (2006) Body burdens of mercury in lower Hudson River area anglers. Environ Res 101:205-12