Principal Investigator/Program Director: Evans, Christopher J., Ph.D., CSORDA Mouse Core CORE: CSORDA Mouse Core ABSTRACT: The CSORDA Mouse Core (CMC) will coordinate and oversee the animal needs of all projects in the Center conducted at UCLA. It will maintain all mutant animal lines needed by the center and make a reliable supply of these animals available to all Center research components. The CMC will also genotype mutant animals used in by the Center for breeding and research. All the Projects of CSORDA will make extensive use of mice, particularly those coming from genetically modified lines. The purpose of the CSORDA Mouse Core (CMC) is to provide these research subjects to all the Components of the Center. The CMC will establish and maintain lines of genetically manipulated mice for use by the Components. The CMC was established in the previous finding cycle and developed a solid set of standardized procedures to accomplish this goal. The CMC continually consults with all Components in the Center about which particular strains of mice are needed and the numbers required to meet the demands of proposed experiments within those Components.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA005010-23
Application #
7899857
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2009-06-01
Budget End
2010-05-31
Support Year
23
Fiscal Year
2009
Total Cost
$208,469
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Ben Hamida, Sami; Mendonça-Netto, Sueli; Arefin, Tanzil Mahmud et al. (2018) Increased Alcohol Seeking in Mice Lacking Gpr88 Involves Dysfunctional Mesocorticolimbic Networks. Biol Psychiatry 84:202-212
Lee, Kevin; Vuong, Helen E; Nusbaum, David J et al. (2018) The gut microbiota mediates reward and sensory responses associated with regimen-selective morphine dependence. Neuropsychopharmacology 43:2606-2614
Maroteaux, G; Arefin, T M; Harsan, L-A et al. (2018) Lack of anticipatory behavior in Gpr88 knockout mice showed by automatized home cage phenotyping. Genes Brain Behav 17:e12473
Ehrlich, Aliza T; Semache, Meriem; Bailly, Julie et al. (2018) Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing. Brain Struct Funct 223:1275-1296
Severino, Amie; Chen, Wenling; Hakimian, Joshua K et al. (2018) Mu-opioid receptors in nociceptive afferents produce a sustained suppression of hyperalgesia in chronic pain. Pain 159:1607-1620
Becker, Jérôme A J; Kieffer, Brigitte L; Le Merrer, Julie (2017) Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol. Addict Biol 22:1205-1217
Bakhurin, Konstantin I; Goudar, Vishwa; Shobe, Justin L et al. (2017) Differential Encoding of Time by Prefrontal and Striatal Network Dynamics. J Neurosci 37:854-870
Lalanne, L; Ayranci, G; Filliol, D et al. (2017) Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence. Addict Biol 22:1010-1021
Dagnew, Robel; Lin, Yin-Ying; Agatep, Jerikko et al. (2017) CerebraLux: a low-cost, open-source, wireless probe for optogenetic stimulation. Neurophotonics 4:045001
Boulos, Laura-Joy; Darcq, Emmanuel; Kieffer, Brigitte Lina (2017) Translating the Habenula-From Rodents to Humans. Biol Psychiatry 81:296-305

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