The objective of this research project is to characterize disruptions of real-time access to lexical information in aphasia. The studies we propose are directed specifically to an analysis of early processing stages in which lexical entries are activated and their meanings and structural properties made available for further processing at the syntactic and semantic levels. Our analyses of lexical activation will take two forms. One set of studies will focus on the time course of activation; a second set, on levels of activation and the role of summation processes within lexical networks. In each case, an attempt will be made to determine if disruptions in these processes are related to the clinical, linguistic, and neuroanatomical characteristics of the aphasic patients tested.

Project Start
1999-12-01
Project End
2001-12-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
35
Fiscal Year
2000
Total Cost
$190,312
Indirect Cost
Name
Boston University
Department
Type
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Zeng, Yong; Petralia, Ronald S; Vijayasarathy, Camasamudram et al. (2016) Retinal Structure and Gene Therapy Outcome in Retinoschisin-Deficient Mice Assessed by Spectral-Domain Optical Coherence Tomography. Invest Ophthalmol Vis Sci 57:OCT277-87
Kurowski, Kathleen; Blumstein, Sheila E (2016) Phonetic basis of phonemic paraphasias in aphasia: Evidence for cascading activation. Cortex 75:193-203
Mirman, Daniel; Yee, Eiling; Blumstein, Sheila E et al. (2011) Theories of spoken word recognition deficits in aphasia: evidence from eye-tracking and computational modeling. Brain Lang 117:53-68
Myung, Jong-yoon; Blumstein, Sheila E; Yee, Eiling et al. (2010) Impaired access to manipulation features in Apraxia: evidence from eyetracking and semantic judgment tasks. Brain Lang 112:101-12
Kurowski, Kathleen M; Blumstein, Sheila E; Palumbo, Carole L et al. (2007) Nasal consonant production in Broca's and Wernicke's aphasics: speech deficits and neuroanatomical correlates. Brain Lang 100:262-75
Connor, L (2001) Memory in old age: patterns of decline and preservation. Semin Speech Lang 22:117-25