Abstract

This Clinical Research Center grant renewal application proposes long-term support for an ongoing program of research on the classification and course of the schizophrenias conducted at the Maryland Psychiatric Research Center. The assumption that schizophrenia is heterogeneous with respect to etiology, manifestations, and course forms a basis for a comprehensive scientific approach to the differentiation and characterization of various subtypes of the disorder. Patients are drawn from the Inpatient and Outpatient Programs of the Maryland Psychiatric Research Center. Support services for CRC investigators will be provided through the following five modules, or cores: Scientific Support, Assessment, Data Management, Clinical Biochemistry Laboratory, and Patient and Subject Recruitment. A separately funded Training Core is an additional component of the proposed program.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH040279-05
Application #
3107128
Study Section
Special Emphasis Panel (SRCM)
Project Start
1986-02-15
Project End
1993-07-31
Budget Start
1991-08-01
Budget End
1992-07-31
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Kelly, Deanna L; McMahon, Robert P; Wehring, Heidi J et al. (2011) Cigarette smoking and mortality risk in people with schizophrenia. Schizophr Bull 37:832-8
Warren, Kimberly R; Ball, M Patricia; Feldman, Stephanie et al. (2011) Exercise program adherence using a 5-kilometer (5K) event as an achievable goal in people with schizophrenia. Biol Res Nurs 13:383-90
Wehring, Heidi J; Liu, Fang; McMahon, Robert P et al. (2010) The relationship of brain weight to body mass index (BMI) upon autopsy in young people with severe mental illness. Schizophr Res 123:86-7
Kelly, Deanna L; McMahon, Robert P; Liu, Fang et al. (2010) Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: a retrospective cohort study. J Clin Psychiatry 71:304-11
Kelly, D L; Weiner, E; Ball, M P et al. (2009) Remission in schizophrenia: the relationship to baseline symptoms and changes in symptom domains during a one-year study. J Psychopharmacol 23:436-41
Kelly, Deanna L; Wehring, Heidi J; Linthicum, Jared et al. (2009) Cardiac-related findings at autopsy in people with severe mental illness treated with clozapine or risperidone. Schizophr Res 107:134-8
McMahon, Robert P; Kelly, Deanna L; Boggs, Douglas L et al. (2008) Feasibility of reducing the duration of placebo-controlled trials in schizophrenia research. Schizophr Bull 34:292-301
Boggs, Douglas L; Kelly, Deanna L; Love, Raymond C et al. (2008) Comparison of clozapine response for inpatients in the research setting versus routine clinical practice. Psychiatr Q 79:111-9
Kelly, Deanna L; Conley, Robert R; Love, Raymond C et al. (2008) Metabolic risk with second-generation antipsychotic treatment: a double-blind randomized 8-week trial of risperidone and olanzapine. Ann Clin Psychiatry 20:71-8
Kelly, Deanna L; Kreyenbuhl, Julie; Dixon, Lisa et al. (2007) Clozapine underutilization and discontinuation in African Americans due to leucopenia. Schizophr Bull 33:1221-4

Showing the most recent 10 out of 21 publications