Abstract

This is a competitive renewal application for the UR-NIMH Clinical Research Center for the Study of Psychopathology of the Elderly (CRC/PE). The CRC/PE endeavors to bring neuropsychiatric research methods to bear upon the study of geriatric psycbopatbology by for-using thematically upon discrete behavioral disturbances and behavior-brain relationships. During the coming five years, we will pursue the following broad goals: (1) establish and conduct multidisciplinary, clinical and laboratory research to further understand the neurobiological bases of abnormal behavior in the elderly; (2) maintain and strengthen our unique, collaborative research setting, and continue to provide support for case identification and follow-up, biostatistical consultation, and data management; (3) coordinate research programs in the University which deal with behavior disorders in the elderly, (4) continue our education and training programs; and (5) vigorously support related new research efforts. The CRC/PE is composed of five cores, including Administrative, Data Management/ Biostatistics, Research Clinical Assessment, Brain Acquisition, and Education/Training; and four research laboratories, including Psychopharmacology (LPP), Neuropsychology (LNP), Suicide Studies (LSS), and Neuroscience (LNS).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH040381-05
Application #
3107141
Study Section
Special Emphasis Panel (SRCM (25))
Project Start
1986-09-15
Project End
1992-08-31
Budget Start
1990-09-01
Budget End
1991-08-31
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Lyness, J M; Conwell, Y; King, D A et al. (1997) Ruminative thinking in older inpatients with major depression. J Affect Disord 46:273-7
Kieburtz, K; Ketonen, L; Cox, C et al. (1996) Cognitive performance and regional brain volume in human immunodeficiency virus type 1 infection. Arch Neurol 53:155-8
Lyness, J M; Conwell, Y; King, D A et al. (1995) Age of onset and medical illness in older depressed inpatients. Int Psychogeriatr 7:63-73
Lyness, J M; Cox, C; Curry, J et al. (1995) Older age and the underreporting of depressive symptoms. J Am Geriatr Soc 43:216-21
Felten, S Y; Felten, D L (1994) Neural-immune interactions. Prog Brain Res 100:157-62
Lyness, J M; Conwell, Y; Nelson, J C (1992) Suicide attempts in elderly psychiatric inpatients. J Am Geriatr Soc 40:320-4
Patel, S; Tariot, P N; Hamill, R W (1991) Pisa syndrome without neuroleptic exposure in a patient with dementia of the Alzheimer type. J Geriatr Psychiatry Neurol 4:48-51