The major objective of the proposed AIDS Psychosocial Research Center is to conduct a coordinated, multidisciplinary, investigate effort into the biopsychosocial aspects of Acquired Immune Deficiency Syndrome (AIDS). It is our contention that by studying the interaction of psychosocial and neuropsychological variables, we can enhance our understanding of the disease and the progression (or lack thereof) of the HTLV-III infection. The proposed AIDS Research Center is organized into core and individual studies. The Center will include administrative, immunologic, psychological and data management cores. The core will support and facilitate the work of eight investigative teams. The individual research studies proposed by these teams are designed to address various aspects of the Center's research aims; by sharing measurements, to foster research synergism. Target groups for the studies include intravenous drug users, male homosexuals and children who are seropositive for the AIDS virus, and minority groups at risk. The investigations themselves range from epidemiologic studies to psychosocial aspects of intervention to dementia and developmental change, studies of community reaction to the disorder, the effect of emotional events and nutritional behavior, their implication for the progression of infection are also central features in this proposal. Close ties to the research, clinical and wider community are an important component on the center research and dissemination strategy. The disciplines involve, but are not limited to, anthropology, psychology, sociology, psychiatry, immunology, neurology, psychology, nutrition, epidemiology and nuclear medicine.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
1P50MH042455-01
Application #
3107174
Study Section
(SRCM)
Project Start
1986-09-30
Project End
1991-02-28
Budget Start
1986-09-30
Budget End
1987-02-28
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33101
Baum, M K (2000) Role of micronutrients in HIV-infected intravenous drug users. J Acquir Immune Defic Syndr 25 Suppl 1:S49-52
Baum, M K; Shor-Posner, G; Lai, S et al. (1997) High risk of HIV-related mortality is associated with selenium deficiency. J Acquir Immune Defic Syndr Hum Retrovirol 15:370-4
Page, J B (1997) Needle exchange and reduction of harm: an anthropological view. Med Anthropol 18:13-33
Page, J B; Lai, S; Fletcher, M A et al. (1996) Predictors of survival in human immunodeficiency virus type 1-seropositive intravenous drug users. Clin Diagn Lab Immunol 3:51-60
Gay, C L; Armstrong, F D; Cohen, D et al. (1995) The effects of HIV on cognitive and motor development in children born to HIV-seropositive women with no reported drug use: birth to 24 months. Pediatrics 96:1078-82
Armstrong, F D; Seidel, J F; Swales, T P (1993) Pediatric HIV infection: a neuropsychological and educational challenge. J Learn Disabil 26:92-103
Kumar, M; Kumar, A M; Morgan, R et al. (1993) Abnormal pituitary-adrenocortical response in early HIV-1 infection. J Acquir Immune Defic Syndr 6:61-5
Klimas, N G; Page, J B; Patarca, R et al. (1993) Effects of retroviral infections on immune function in African-American intravenous drug users. AIDS 7:331-5
Fletcher, M A; Klimas, N G; Morgan, R O (1993) Immune function and drug treatment in anti-retrovirus negative intravenous drug users. Adv Exp Med Biol 335:241-6
Beach, R S; Morgan, R; Wilkie, F et al. (1992) Plasma vitamin B12 level as a potential cofactor in studies of human immunodeficiency virus type 1-related cognitive changes. Arch Neurol 49:501-6

Showing the most recent 10 out of 20 publications