Abstract

The overarching principle of this Core will be to support all aspects of study data, from inception of the study aims through publication of the study results, while maintaining the highest standards possible to insure the integrity of the data and the results obtained. To accomplish this, there are four primary functions of this core: Data management, Study design, Data analysis, and Computing. Collectively, these core functions will provide support for all aspects of dealing with data, from study design through data analysis and publication of the results, as well as computing support to facilitate these data functions. The members of the core include biostatisticians, data management and computing professionals, and a bioinformatician. The biostatistical team includes expertise in the design, conduct, and analysis of both human and animal studies as well as imaging data. The informatician will have expertise in the analysis and management of gene expression data. Dr. Warren Bilker will serve as the Core director overseeing all activities and personnel.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
1P50MH064045-01
Application #
6553528
Study Section
Special Emphasis Panel (ZMH1)
Project Start
2001-09-15
Project End
2006-07-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

van Erp, Theo G M; Walton, Esther; Hibar, Derrek P et al. (2018) Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biol Psychiatry 84:644-654
Walton, E; Hibar, D P; van Erp, T G M et al. (2017) Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium. Acta Psychiatr Scand 135:439-447
Barz, Claudia S; Bessaih, Thomas; Abel, Ted et al. (2016) Sensory encoding in Neuregulin 1 mutants. Brain Struct Funct 221:1067-81
Satterthwaite, Theodore D; Wolf, Daniel H; Calkins, Monica E et al. (2016) Structural Brain Abnormalities in Youth With Psychosis Spectrum Symptoms. JAMA Psychiatry 73:515-24
Welle, Cristin G; Contreras, Diego (2016) Sensory-driven and spontaneous gamma oscillations engage distinct cortical circuitry. J Neurophysiol 115:1821-35
Satterthwaite, Theodore D; Connolly, John J; Ruparel, Kosha et al. (2016) The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth. Neuroimage 124:1115-9
Barz, Claudia S; Bessaih, Thomas; Abel, Ted et al. (2016) Altered resonance properties of somatosensory responses in mice deficient for the schizophrenia risk gene Neuregulin 1. Brain Struct Funct 221:4383-4398
Larimore, Jennifer; Zlatic, Stephanie A; Gokhale, Avanti et al. (2014) Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes. J Biol Chem 289:14291-300
Bilker, Warren B; Wierzbicki, Michael R; Brensinger, Colleen M et al. (2014) Development of abbreviated eight-item form of the Penn Verbal Reasoning Test. Assessment 21:669-78
Kohn, Nils; Falkenberg, Irina; Kellermann, Thilo et al. (2014) Neural correlates of effective and ineffective mood induction. Soc Cogn Affect Neurosci 9:864-72

Showing the most recent 10 out of 118 publications