Abstract

The overall objective of the MRI Core is to provide comprehensive state-of-the-art MRI support for clinical and experimental projects and ensure further improvement of data acquisition and analysis. Objectives: To provide Magnetic Resonance Imaging (MRI) to support all projects. To improve MRI acquisition and analysis for human and rodent neonatal studies. In concert with the individual Projects and the Behavior Core, provide data analysis of injury evolution in relation to neurobehavior and histological outcomes. To relate the diffusion data acquired in the animal studies with those acquired in the human newborns. These objectives will be accomplished in both humans and rodents.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
2P50NS035902-06
Application #
6688213
Study Section
Special Emphasis Panel (ZNS1)
Project Start
2002-09-25
Project End
2007-08-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Peyvandi, Shabnam; Kim, Hosung; Lau, Joanne et al. (2018) The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease. J Thorac Cardiovasc Surg 155:291-300.e3
van Velthoven, Cindy T; Dzietko, Mark; Wendland, Michael F et al. (2017) Mesenchymal stem cells attenuate MRI-identifiable injury, protect white matter, and improve long-term functional outcomes after neonatal focal stroke in rats. J Neurosci Res 95:1225-1236
Desikan, Rahul S; Barkovich, A James (2016) Malformations of cortical development. Ann Neurol 80:797-810
Kansagra, Akash P; Mabray, Marc C; Ferriero, Donna M et al. (2016) Microstructural maturation of white matter tracts in encephalopathic neonates. Clin Imaging 40:1009-13
Peyvandi, Shabnam; De Santiago, Veronica; Chakkarapani, Elavazhagan et al. (2016) Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury. JAMA Pediatr 170:e154450
Gano, Dawn; Ho, Mai-Lan; Partridge, John Colin et al. (2016) Antenatal Exposure to Magnesium Sulfate Is Associated with Reduced Cerebellar Hemorrhage in Preterm Newborns. J Pediatr 178:68-74
Larpthaveesarp, Amara; Georgevits, Margaret; Ferriero, Donna M et al. (2016) Delayed erythropoietin therapy improves histological and behavioral outcomes after transient neonatal stroke. Neurobiol Dis 93:57-63
Gano, Dawn; Andersen, Sarah K; Glass, Hannah C et al. (2015) Impaired cognitive performance in premature newborns with two or more surgeries prior to term-equivalent age. Pediatr Res 78:323-9
Gano, Dawn; Andersen, Sarah K; Partridge, J Colin et al. (2015) Diminished white matter injury over time in a cohort of premature newborns. J Pediatr 166:39-43
Titomanlio, Luigi; Fernández-López, David; Manganozzi, Lucilla et al. (2015) Pathophysiology and neuroprotection of global and focal perinatal brain injury: lessons from animal models. Pediatr Neurol 52:566-584

Showing the most recent 10 out of 93 publications