The Clinical Physiology Core will be co-directed by Drs. E.T. Poehlman and D. Elahi. The major goal(s) of the Core are to provide support for the Intervention Studies and Pilot Projects with the following services: 1) To provide a """"""""gatekeeper"""""""" function in which patients will be properly characterized and screened on a clinical level and physiological level prior to entering the Intervention Studies, 2) To provide standardized and quality controlled measures of cardiovascular function, body composition, body fat distribution, musculoskeletal function, energy metabolism, and kinetic behavior of substrates and hormones and 3) To provide an educational and consultative resource relative to Clinical Physiology methodologies to all investigators and research projects. The Clinical Physiology Facility will formalize and centralize existing facilities under one-state-of-the-art facility, thus ensuring financial stability, expert quality control and availability of services to investigators interested in gerontology/geriatric research. In addition, the Clinical Physiology Core will provide the necessary clinical/physiology research training for junior investigators, including predoctoral, postdoctoral and junior faculty interested in clinical research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
5P60AG012583-03
Application #
5204975
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Addison, Odessa; Prior, Steven J; Kundi, Rishi et al. (2018) Sarcopenia in Peripheral Arterial Disease: Prevalence and Effect on Functional Status. Arch Phys Med Rehabil 99:623-628
Woytowicz, Elizabeth J; Rietschel, Jeremy C; Goodman, Ronald N et al. (2017) Determining Levels of Upper Extremity Movement Impairment by Applying a Cluster Analysis to the Fugl-Meyer Assessment of the Upper Extremity in Chronic Stroke. Arch Phys Med Rehabil 98:456-462
Addison, Odessa; Ryan, Alice S; Prior, Steven J et al. (2017) Changes in Function After a 6-Month Walking Intervention in Patients With Intermittent Claudication Who Are Obese or Nonobese. J Geriatr Phys Ther 40:190-196
Ortmeyer, Heidi K; Goldberg, Andrew P; Ryan, Alice S (2017) Exercise with weight loss improves adipose tissue and skeletal muscle markers of fatty acid metabolism in postmenopausal women. Obesity (Silver Spring) 25:1246-1253
Addison, Odessa; Inacio, Mario; Bair, Woei-Nan et al. (2017) Role of Hip Abductor Muscle Composition and Torque in Protective Stepping for Lateral Balance Recovery in Older Adults. Arch Phys Med Rehabil 98:1223-1228
Kundi, Rishi; Prior, Steven J; Addison, Odessa et al. (2017) Contrast-Enhanced Ultrasound Reveals Exercise-Induced Perfusion Deficits in Claudicants. J Vasc Endovasc Surg 2:
Resnick, Barbara; Gruber-Baldini, Ann L; Hicks, Gregory et al. (2016) Measurement of Function Post Hip Fracture: Testing a Comprehensive Measurement Model of Physical Function. Rehabil Nurs 41:230-47
Kisser, Jason E; Allen, Allyssa J; Katzel, Leslie I et al. (2016) Relations of blood pressure and head injury to regional cerebral blood flow. J Neurol Sci 365:9-14
Resnick, Barbara; Beaupre, Lauren; McGilton, Katherine S et al. (2016) Rehabilitation Interventions for Older Individuals With Cognitive Impairment Post-Hip Fracture: A Systematic Review. J Am Med Dir Assoc 17:200-5
Addison, Odessa; Steinbrenner, Gregory; Goldberg, Andrew P et al. (2015) Aging, Fitness, and Marathon Times in a 91 Year-old Man Who Competed in 627 Marathons. Br J Med Med Res 8:1074-1079

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