The Data Acquisition Core (DAC) is a centralized coordinating facility for the collection of data in education, epidemiology, and health services research (EEHSR) projects funded through the Indiana University Multipurpose Arthritis and Musculoskeletal Diseases Center (IUMAMDC). All four proposed EEHSR projects and two of the five proposed Developmental and Feasibility (D&F) Studies will gather data through structured interviews, both at various sites on the Indiana University Medical center Campus and at remote sites in the community. Therefore, the specific aims of the Data Acquisition Core (DAC) will be as follows: 1. To provide EEHSR and other clinical arthritis investigators with the resources necessary to train study coordinators and interviewers in their research protocols; 2. To schedule and conduct subject screening and data collection sessions according to project protocols, and to edit and code data from completed interviews; and 3. To serve as a data acquisition facility for future investigations in arthritis-related educational, epidemiological, and health services research. To provide for the data acquisition needs of EEHSR and other clinical arthritis investigators, the DAC supports the partial effort of a Core Director, a full-time Project Manager, a sufficient number of full- time equivalent (FTE) Study Coordinators to execute current study protocols, and specialized technical personnel (e.g., physical therapy assistants) required, as needed, by projects to supplement the effort and expertise of the Study Coordinators.

Project Start
1999-04-01
Project End
2000-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
22
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Mazzuca, Steven A; Brandt, Kenneth D; Katz, Barry P et al. (2007) Risk factors for early radiographic changes of tibiofemoral osteoarthritis. Ann Rheum Dis 66:394-9
Merle-Vincent, F; Vignon, E; Brandt, K et al. (2007) Superiority of the Lyon schuss view over the standing anteroposterior view for detecting joint space narrowing, especially in the lateral tibiofemoral compartment, in early knee osteoarthritis. Ann Rheum Dis 66:747-53
Otterness, Ivan G; Brandt, Kenneth D; Le Graverand, Marie-Pierre Hellio et al. (2007) Urinary TIINE concentrations in a randomized controlled trial of doxycycline in knee osteoarthritis: implications of the lack of association between TIINE levels and joint space narrowing. Arthritis Rheum 56:3644-9
Mazzuca, S A; Brandt, K D; Eyre, D R et al. (2006) Urinary levels of type II collagen C-telopeptide crosslink are unrelated to joint space narrowing in patients with knee osteoarthritis. Ann Rheum Dis 65:1055-9
Brandt, Kenneth D; Mazzuca, Steven A (2006) Experience with a placebo-controlled randomized clinical trial of a disease-modifying drug for osteoarthritis: the doxycycline trial. Rheum Dis Clin North Am 32:217-34, xi-xii
Mazzuca, S A; Brandt, K D; Katz, B P et al. (2006) Comparison of quantitative and semiquantitative indicators of joint space narrowing in subjects with knee osteoarthritis. Ann Rheum Dis 65:64-8
Mazzuca, Steven A; Poole, A Robin; Brandt, Kenneth D et al. (2006) Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis. J Rheumatol 33:1147-51
Mikesky, Alan E; Mazzuca, Steven A; Brandt, Kenneth D et al. (2006) Effects of strength training on the incidence and progression of knee osteoarthritis. Arthritis Rheum 55:690-9
Hellio Le Graverand, M-P; Brandt, K D; Mazzuca, S A et al. (2006) Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis. Osteoarthritis Cartilage 14:1189-95
Brandt, Kenneth D; Mazzuca, Steven A; Katz, Barry P et al. (2005) Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial. Arthritis Rheum 52:2015-25

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