Degenerative disease of the cervical spine is common in the US population and causes significant morbidity and expense. Of the patients who ultimately come to surgery (70,000 per year), many have CT-myelography (CTM). an invasive procedure which is expensive and carries some risks. Nearly all of these patients will also have had magnetic resonance imaging (MRI). We propose to use new methods for 3D image fusion to create fused images from MRI scans and plain CT scans (i.e., without myelography) of the neck, potentially saving $15-30 million in healthcare costs per year. We hypothesize that these fused CT-MRI images will be equivalent for both diagnostic and surgical planning purposes to CTM and MRI. This hypothesis will be tested using MRI and plain CT scans from 50 consecutive patients undergoing both CTM and MRI and comparing the diagnoses and surgical plans formulated from the fused images to those formulated using MRI and CTM. Plans and diagnoses will be evaluated by panels of 7 spine surgeons and 4 neuroradiologists, respectively. Statistical evaluation of the systematic differences in plans and diagnoses, if present, will also be performed.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
1P60AR048093-01
Application #
6574626
Study Section
Special Emphasis Panel (ZAR1)
Project Start
2002-02-15
Project End
2006-12-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Manoso, Mark W; Cizik, Amy M; Bransford, Richard J et al. (2014) Medicaid status is associated with higher surgical site infection rates after spine surgery. Spine (Phila Pa 1976) 39:1707-13
Mirza, Sohail K; Deyo, Richard A; Heagerty, Patrick J et al. (2013) One-year outcomes of surgical versus nonsurgical treatments for discogenic back pain: a community-based prospective cohort study. Spine J 13:1421-33
Lee, Michael J; Konodi, Mark A; Cizik, Amy M et al. (2013) Risk factors for medical complication after cervical spine surgery: a multivariate analysis of 582 patients. Spine (Phila Pa 1976) 38:223-8
Hacquebord, Jacques; Cizik, Amy M; Malempati, Sree Harsha et al. (2013) Medicaid status is associated with higher complication rates after spine surgery. Spine (Phila Pa 1976) 38:1393-400
Baker, Geoff A; Cizik, Amy M; Bransford, Richard J et al. (2012) Risk factors for unintended durotomy during spine surgery: a multivariate analysis. Spine J 12:121-6
Lee, Michael J; Konodi, Mark A; Cizik, Amy M et al. (2012) Risk factors for medical complication after spine surgery: a multivariate analysis of 1,591 patients. Spine J 12:197-206
Hu, Yangqiu; Ledoux, William R; Fassbind, Michael et al. (2011) Multi-rigid image segmentation and registration for the analysis of joint motion from three-dimensional magnetic resonance imaging. J Biomech Eng 133:101005
Lee, Michael J; Hacquebord, Jacques; Varshney, Anuj et al. (2011) Risk factors for medical complication after lumbar spine surgery: a multivariate analysis of 767 patients. Spine (Phila Pa 1976) 36:1801-6
Hsu, Clarissa; Bluespruce, June; Sherman, Karen et al. (2010) Unanticipated benefits of CAM therapies for back pain: an exploration of patient experiences. J Altern Complement Med 16:157-63
Deyo, Richard A; Mirza, Sohail K; Turner, Judith A et al. (2009) Overtreating chronic back pain: time to back off? J Am Board Fam Med 22:62-8

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