Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Transition Award (R00)
Project #
3R00CA129613-03S1
Application #
7935544
Study Section
Subcommittee G - Education (NCI)
Program Officer
Spalholz, Barbara A
Project Start
2009-09-30
Project End
2010-09-29
Budget Start
2009-09-30
Budget End
2010-09-29
Support Year
3
Fiscal Year
2009
Total Cost
$86,000
Indirect Cost

  Institution

Name
University of Massachusetts Medical School Worcester
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655

  Publications

Hung, Chien-Min; Calejman, Camila Martinez; Sanchez-Gurmaches, Joan et al. (2014) Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease. Cell Rep 8:256-71
Sanchez-Gurmaches, Joan; Guertin, David A (2014) Adipocyte lineages: tracing back the origins of fat. Biochim Biophys Acta 1842:340-51
Hung, Chien-Min; Garcia-Haro, Luisa; Sparks, Cynthia A et al. (2012) mTOR-dependent cell survival mechanisms. Cold Spring Harb Perspect Biol 4:
Sanchez-Gurmaches, Joan; Hung, Chien-Min; Sparks, Cynthia A et al. (2012) PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab 16:348-62
Li, Huawei; Cotton, Jennifer L; Guertin, David A (2012) Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics. Methods Mol Biol 821:329-47
Kalaitzidis, Demetrios; Sykes, Stephen M; Wang, Zhu et al. (2012) mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell 11:429-39
Sparks, C A; Guertin, D A (2010) Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy. Oncogene 29:3733-44