This research training project will address three major questions in contemporary research on health and well- being: (1) how do social exposures manifest in physiological processes leading to disease, disability, and death? (2) Which characteristics predispose individuals to faster or slower rates of decline in health over the life course? (3) What coping strategies are most effective at preventing declines in health (resilience) or aid in improvements in health status following health insults (recovery)? Identification of causal effects is a key challenge in the health and mortality literature. Without appropriate data and credible means of identifying causal effects, it is not clear how to interpret associations between exposures and health. There has been explosive growth in the extent and depth of biological information (biomarkers providing quantified measures of physiological states) collected in large scale population surveys. The richness of these data are unlikely to be fully exploited without greater integration of psychosocial and biological mechanisms in models of population processes that describe biologically plausible causal pathways. This project is designed to contribute to filling this gap by providing the candidate, a demographer and sociologist, with the necessary skills and experience to significantly advance population health research. First, she will complete training in the biological foundations of health that will complement her training in demography. Second, she will complete formal training in causal analysis with particular reference to population health in developing countries. Third, she will obtain hands-on training and experience in the collection and use of biomarkers in health research in a low income setting. The proposed research project will examine the health impacts of three large scale events: the 1997 Asian financial crisis in Indonesia, the 2004 Indian Ocean tsunami in Indonesia, and the post 2006 rise in violent crime in Mexico. These analyses will draw on three unique, population-representative longitudinal surveys fielded in Indonesia (IFLS and STAR) and Mexico (MxFLS) which include a rich set of biological and psychosocial health measures and collect information prior to and following these events. Using these datasets and methods of causal analysis, the candidate will examine how exposure to these arguably exogenous events affects health and well-being in the short-, medium-, and long-term; identify individual, household, and community characteristics predicting resilience and recovery from these events; and evaluate whether the type of exposure experienced during the event (e.g., loss of family members vs. loss of housing vs. loss of other assets) offers insight into the specific mechanisms through which these exposures impact health. An innovative component of this project involves the candidate undertaking a new data collection effort collecting new social isolation and biomarker measures in Indonesia specifically designed for this research project. Analyses of these data will enrich understanding of the interplay between biological and psychosocial health.

Public Health Relevance

Promoting health and well-being over the life course worldwide is a key public health priority, and understanding the factors contributing to declines and recovery in health and well-being over individuals' lives is essential to meeting this goal. This project seeks to identify the short-, medium-, and long-term impacts of exposure to three large scale natural and man-made disasters (the 1997 Asian financial crisis in Indonesia, the 2004 Indian Ocean tsunami in Indonesia, and the post 2006 rise in violent crime in Mexico) on multiple dimensions of health and well-being. Particular emphasis will be placed on understanding the individual, household, and community baseline characteristics and the coping mechanisms they employ that contribute to resilience and recovery in health status among individuals exposed to these events, as well as on the interactions between biological and psychosocial health.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Transition Award (R00)
Project #
5R00HD083519-05
Application #
9737717
Study Section
Special Emphasis Panel (NSS)
Program Officer
King, Rosalind B
Project Start
2017-08-01
Project End
2020-07-31
Budget Start
2019-08-01
Budget End
2020-07-31
Support Year
5
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
Other Specialized Schools
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Ho, Jessica Y; Frankenberg, Elizabeth; Sumantri, Cecep et al. (2017) Adult Mortality Five Years after a Natural Disaster. Popul Dev Rev 43:467-490
Ho, Jessica Y (2017) The Contribution of Drug Overdose to Educational Gradients in Life Expectancy in the United States, 1992-2011. Demography 54:1175-1202
Peltonen, Riina; Ho, Jessica Y; Elo, Irma T et al. (2017) Contribution of smoking-attributable mortality to life expectancy differences by marital status among Finnish men and women, 1971-2010. Demogr Res 36:255-280